Page 785 - Problem-Based Feline Medicine
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34 – THE CAT WITH SIGNS OF LARGE BOWEL DIARRHEA  777


           On rectal examination there are impacted feces in a rec-  Cats often will lick at the area frequently which may
           tal dilation or sacculation, and evidence of a defect in  draw attention to the region.
           the pelvic diaphragm musculature.
                                                          Diagnosis
           Diagnosis                                      In the majority of cases, the presence of a perianal mass
           The diagnosis may be suggested by the  history or  will be the obvious cause of the intestinal disturbance.
           appearance of the perineal area and a rectal exami-  Perianal tumors may metastasize locally (to regional
           nation will confirm the problem in many cases.  lymph nodes or bones) or to distant sites (liver, lung or
           In cases where the diagnosis is in doubt, a  barium  abdominal sites) and so, a  routine database, radio-
           enema will outline the herniated rectal tissue.  graphs and ultrasound, and fine-needle aspirates of
                                                          regional or enlarged lymph nodes should be per-
           These hernias are rare in cats compared to dogs.  formed.
                                                          Fine-needle aspirates of the tumor can be used to iden-
           Treatment                                      tify the tumor type prior to surgical biopsy.

           Medical management using low-residue food and fecal
           softeners (e.g. lactulose) or enemas may help in cats  Differential diagnosis
           with small hernias.
                                                          The primary differential for this problem is anal sac-
           Surgery is considered the preferred treatment and  culitis or abscess, which are more common problems,
           several herniorrhaphy techniques have been described,  but generally are less likely to cause problems with
           although recurrence rates can be high (10–50%). In cats  fecal passage.
           with megacolon, subtotal colectomy may resolve the
           constipation and tenesmus. Herniorraphy can be
                                                          Treatment
           performed in cats that do not improve with medical
           therapy.                                       Surgical resection of tumor with  wide margins to
                                                          prevent recurrence.
           PERIANAL TUMORS                                Histopathologic examination of the tumor as well as
                                                          biopsies of regional lymph nodes is recommended for
            Classical signs                               confirmation of the diagnosis and determination of
                                                          the prognosis.
            ● Straining to defecate.
            ● Large bowel diarrhea or constipation.       Fecal softeners (e.g. lactulose or docusate sodium) may
            ● Perineal swelling.                          be helpful if fecal material is difficult or painful to pass.
            ● Licking excessively at the perineum.
                                                          PSEUDOMEMBRANEOUS COLITIS
                                                          (ANTIBIOTIC-INDUCED COLITIS)
           Pathogenesis
           These tumors occur more commonly in older cats.  Classical signs

           Tumors of the perianal region in cats, unlike those in  ● Mucus- or blood-streaked, soft (semi-
           dogs, are usually  adenocarcinomas. Perianal tumors  formed) feces.
           are very rare in cats compared to dogs.         ● Progression to severe large bowel
                                                             diarrhea.
           Clinical signs
                                                          Pathogenesis
           Straining to defecate, large bowel diarrhea, perineal
           swelling, or constipation may all occur due to large  This disease is caused by the use of antibiotics (espe-
           perianal mass(es).                             cially clindamycin or cephalosporins) that disturb the
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