Page 847 - Problem-Based Feline Medicine
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38 – THE CAT WITH A HEAD TILT, VESTIBULAR ATAXIA OR NYSTAGMUS  839


              severity of the inflammation. Although inflamma-
                                                           DISEASES CAUSING A HEAD TILT,
              tory diseases are multifocal or diffuse pathologi-
                                                           VESTIBULAR ATAXIA OR
              cally, this is often not the case clinically, where the
                                                           NYSTAGMUS
              neurological deficits in most cases can be assigned
              to one location.
                                                          IDIOPATHICVESTIBULAR SYNDROME***
           Diagnosis is based on careful history taking (to dis-
           close if there is somnolence or quietness of the ani-
                                                           Classical signs
           mal), physical, neurological, otoscopic and
           ophthalmoscopic (including Schirmer tear test)  ● Acute to subacute onset of a head tilt,
           examinations, serum protein concentration, cere-  falling, rolling and nystagmus.
           brospinal fluid analysis (CSF), CSF anti-coronavirus  ● Disorientation can be severe with the cat
           IgG titer, electrodiagnostic testing (brain auditory-  unwilling to move and crying out with
           evoked responses), bullae radiography, computed   anxiety.
           tomography (CT) and magnetic resonance imaging  ● Otherwise healthy cat.
           (MRI) scan.
           Reference ranges for feline CSF.               Pathogenesis
                             9
            ● RBC < 0.030 × 10 /L (30/μl)
                             9
            ● WBC ≤ 0.002 × 10 /L (2/μl)                  Unknown.
            ● Cytology (%)
                                                          Clinical signs
              – Monocytoid cells 69–100%
              – Lymphocytes 0–27%                         Possibly higher incidence in July and August in north-
              – Neutrophils 0–9%                          east United States.
              – Eosinophils 0
              – Macrophages (large foamy mononuclear cells)  Cats of any age or sex, median age is 4 years old.
                0–3%                                      Acute, non-progressive, unilateral and occasionally
            ● Protein 0.036 g/L (36 mg/dl)                bilateral, peripheral vestibular disturbance.

           It is good practice to request electrodiagnostic testing  The head tilt, ataxia and nystagmus (most often hori-
           (BAER) to evaluate for deafness. If deafness is con-  zontal) can be severe with the animal crying out with
           comitantly present, it is an indication of a more aggres-  anxiety, reluctant to walk, remaining in a crouched pos-
           sive disorder and a thorough diagnostic work up should  ture or with wide abduction of the limbs.
           be pursued.
                                                          Rarely, can be bilateral.
           When a head tilt is present, or when there is facial
                                                          Vomiting occasionally occurs, usually soon after onset
           paresis/paralysis or a Horner’s syndrome, bulla radi-
                                                          of signs.
           ography is recommended to evaluate the middle
           ear cavities. An open mouth view is best to compare  Affected cats are otherwise healthy.
           the density between the bullae. Bulla radiography is
           not a sensitive tool. It may be normal despite the pres-  Diagnosis
           ence of disease. Computed tomography (CT) scan of
                                                          History of an acute to subacute onset, in a previously
           the bullae is superior and should be done when avail-
                                                          healthy cat, of severe disorientation, falling and rolling,
           able.
                                                          that improves rapidly (a few days to 2 weeks) and with-
           Regardless of the cause of the vestibular signs, nystag-  out treatment.
           mus and vestibular ataxia usually resolve, but the head
                                                          The cat is otherwise healthy and has no other neurolog-
           tilt usually persists for the life of the animal. It may
                                                          ical signs.
           be barely noticeable but may be  exacerbated after
           a general anesthetic or when the cat is ill.   The otoscopic examination is unremarkable.
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