Page 998 - Problem-Based Feline Medicine
P. 998

990   PART 11  CAT WITH AN ABNORMAL GAIT



           Classical signs—Cont’d                       They often display an abnormal posture with a stiff
                                                        neck and gait.
           ● Varying degrees of severity of the
             condition exist.
                                                        Diagnosis
         See main references on page 920 for details (The Weak
                                                        Radiographically there is ankylosis of cervical and
         and Ataxic or Paralyzed Cat).
                                                        cranial thoracic vertebra, and new bone proliferation
                                                        around shoulder and elbow joints.
         Clinical signs
                                                        History of diet almost exclusively of liver.
         Improper closure of the neural tube during embryogenesis
         occurs, with varying severity of neurological signs seen
                                                        Treatment
         affecting hindlimb function and urinary and fecal control.
                                                        Correction of the diet, ideally on a balanced commer-
         In the Manx cat it is often associated with sacral
                                                        cial diet.
         dysgenesis.
                                                        May require short-term analgesics.
         Diagnosis
                                                        Prognosis
         Based on clinical signs, radiographic findings.
                                                        Correction of the diet halts the progression of disease,
                                                        and some remodeling of existing bone may occur.
         HYPERVITAMINOSIS A                             However, bony changes are often permanent and pain
                                                        may persist.
           Classical signs
                                                        NUTRITIONAL HYPERPARATHYROIDISM
           ● Due to excessive intake of vitamin A,
             usually from an all-liver diet.
                                                         Classical signs
           ● Lameness occurs due to bony exostoses
             around the cervical vertebrae and           ● Lameness present in multiple sites in
             ankylosis of joints.                          young kittens.
                                                         ● Due to a diet deficient in calcium, such as
                                                           an all-meat diet.
         Pathogenesis

         Due to excessive vitamin A intake over several months,  Pathogenesis
         usually from an all-liver diet.
                                                        Due to increased parathyroid hormone from persistent
         Causes bony exostoses of spine and osseous hyper-  hypocalcemia, either from an absolute dietary calcium
         plasia and proliferation at joint margins, particularly  deficiency or secondary to excessive phosphorus intake
         the shoulder and elbow joints.                 relative to calcium.
         Excess vitamin A causes increased reactivity of the  Causes generalized osteopenia.
         periosteum, resulting in bony proliferation at sites of
                                                        Most commonly seen in kittens on an all-meat diet.
         joint capsule and soft tissue attachments to bone.
                                                        Occurs with an all-meat diet even if the kittens have
                                                        access to milk.
         Clinical signs
                                                        Clinical signs
         Cats are often reluctant to move around, and are very
         painful.                                       Osteopenia can result in spontaneous fracture.
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