Page 165 - Equine Clinical Medicine, Surgery and Reproduction, 2nd Edition
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140                                        CHAPTER 1



  VetBooks.ir  Aetiology/pathophysiology                  Differential diagnosis
                                                          Fetlock OA; OCD; osteochondral fragmentation;
           POD is thought to relate to repetitive high strains
           on bone and articular tissues in the distal condyles
           of the third metacarpus/metatarsus experienced in   PSB fracture.
           training and racing. Affected cases will show carti-  Diagnosis
           lage wear lines and loss and collapse of the articular   Radiography may reveal minimal signs to changes
           surface with commensurate underlying subchon-  in bone density in the subchondral bone in the distal
           dral bone pathology at post-mortem. Higher POD   and palmar/plantar aspect of the condyles. Changes
           grades have been associated with use of intra-   in bone density include focal radiolucencies in the
           articular corticosteroids (particularly triamcinolone)     palmar/plantar condyles, alteration to the outline
           while in training, whereas lower grades are reported   of the   subchondral bone and sclerosis of the pal-
           in horses with longer intervals between races.  mar condyles. Radiographic projections, including
                                                          flexed dorsopalmar/plantar and elevated oblique
           Clinical presentation                          views, have been used to improve diagnosis of this
           POD is suspected in young racehorses with lameness   condition. In some cases, changes in joint incongru-
           in one or more limbs involving the fetlock region. In   ity may be present with evidence of flattening of the
           some cases there are no signs referable to the fetlock.   condyle (Fig. 1.253). This latter  finding may repre-
           Lameness may range from mild and performance   sent  collapse of the articular surface. Radiographic
           limiting to overt pain localised to the fetlock joint.   evidence of OA may also be present, but this is
           A  better response to perineural rather that intra-    uncommon. On nuclear scintigraphy, horses affected
           articular analgesia often occurs and is likely to be due   with POD will show moderate to marked increased
           to the underlying pathophysiology of the condition.  radiopharmaceutical uptake in the condylar region
                                                          of the fetlock. MRI can be used to differentiate
                                                          POD from other fetlock pathology (e.g. prodromal
           1.253                                          condylar fracture); in one study over 50% of racing
                                                          Thoroughbreds with lameness localised to the fet-
                                                          lock region had signs consistent with POD (often
                                                          biaxially) (Figs. 1.254, 1.255).

                                                          Management
                                                          Although intra-articular  medication is  associated
                                                          with development of POD, it is still commonly
                                                          used in its management. Alterations to training
                                                          regimes can be associated with positive outcomes.
                                                          Short periods of rest, however, may be associated
                                                          with increased severity of POD. This is thought to
                                                          be related to lesions still in the resorptive phase of
                                                          healing, which may lead to severe focal changes on
                                                          return to racing. POD is a common finding at post-
                                                          mortem and likely to be a significant contributor to
                                                          wastage among Thoroughbred racehorses.
           Fig. 1.253  Lateromedial radiograph of the left hind
           fetlock joint in a 5-year-old Thoroughbred flat racehorse   Prognosis
           with bilateral hindlimb lameness. Note the flattening of   Prognosis with this condition can be variable. Mild
           the plantar condyle of the distal third metatarsal bone   cases often resolve but some cases will be recur-
           (arrow), with wedge-shaped subchondral bone sclerosis.   rent. Severity has been linked to reduced race
           (Photo courtesy Graham Munroe)                 starts/earnings.
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