Page 1516 - Clinical Small Animal Internal Medicine
P. 1516

1454  Section 12  Skin and Ear Diseases

            currently no studies evaluating it’s use in the treatment   Description of mite characteristics is important in dif-
  VetBooks.ir  of feline demodicosis. Independent of the parasiticidal   ferentiating  canine  scabies from  the feline  Sarcoptidae
                                                              mite,  Notoedres cati.  Sarcoptes scabei mites are ovoid
            chosen, treatment should be continued for 30 days past
            two consecutive negative skin scrapings performed 4–6
                                                              unjointed stalks and suckers. There are two pairs of
            weeks apart.                                      and small, with two anterior pairs of short legs with long
             Options for  D. gatoi include the above treatment     rudimentary posterior legs that do not extend beyond
              protocols described for amitraz or lime sulfur dips.   the body wall of the mite (Figure  165.7). The anus is
            Treatment  typically is needed for 6–8 weeks. In‐contact   terminal.
            cats should be treated as well. Application of a moxidec-  Research suggests that young dogs of any breed and of
            tin/imidacloprid (Advantage Multi for cats; BayerDVM)   both sexes are more likely to become infested with the
            spot‐on product every week to two weeks for up to three   mites, suggesting that age‐related immunity plays a role
            months has been anecdotally reported to work well in   in pathogenesis. Nutritional status and oxidative stress
            some cases. It has also been shown to be efficacious in   also play a role in development of infestation. Specifically,
            one case report, applied weekly for 10 doses. Also, iver-  alterations in the oxidant and antioxidant balance and
            mectin at 0.2–0.3 mg/kg PO every 24–48 hours may be   greater apoptosis of peripheral leukocytes may contrib-
            effective. The extra-label use of oral fluralaner (Bravecto)   ute to a dog’s susceptibility to infestation.
            at 26–34 mg/kg given once has recently been shown to
            be another efficacious treatment option.          History and Clinical Signs
             No specific treatment recommendations exist for the   Scabies  causes  an  intense  pruritus.  It  is  important  to
            unnamed mite, but concurrent daily ivermectin at   question if other pets or humans in the same household
            0.3 mg/kg PO and 8 oz/gal of diluted lime sulfur rinses   are also pruritic as this  is a valuable diagnostic clue.
            twice weekly for 6–8 weeks has been used. Also, SC iver-  However, some dogs can be asymptomatic carriers. As
            mectin at 0.6 mg/kg daily for four weeks has been used.  previously mentioned, this mite typically affects specific
              For all types of feline demodicosis, isoxazolines may   body regions but any body region can be affected.
            prove to be efficacious. Also, topical fluralaner may be a   Corticosteroids may be beneficial in some patients at the
            viable option as opposed to oral administration. More   beginning of therapy to reduce pruritus.
            studies are needed in this area.                    Early signs include papules and scales. Excoriations
                                                              may also be present. With chronicity, self‐induced alope-
            Prognosis                                         cia, hyperpigmentation, hyperkeratosis or keratinous
            The prognosis of feline demodicosis varies, especially in   crusts, and  lichenification may  develop. The  crusts
            cases of D. cati where underlying systemic disease is likely   may become thick and yellow (Figure 165.8). Peripheral
            present. Overall, prognosis varies from good to guarded.    lymphadenopathy may be present. Some dogs only
                                                              develop erythema and excoriations.

              Scabies


            Canine Scabies
            Etiology/Pathophysiology
            Sarcoptes scabei var.  canis causes canine scabies, or
              sarcoptic mange. This is a highly contagious mite that is
            transmitted between dogs as well as foxes and coyotes.
            Fomites can also be a source of transmission. The female
            burrows into the stratum corneum to lay eggs. The  larvae
            travel to the skin surface and develop into nymphs, which
            may live on the skin surface or in the molting pocket that
            may also be inhabited by larvae. The mites prefer areas
            with less hair, so they are more commonly found on the
            pinnae, elbows, hocks, and ventrum. They typically live
            17–21 days. Depending on the humidity and temperature,
            females and nymphs can survive 4–21 days away from the
            host. These mites can cause disease at any time of year.
            Other animals including cats, humans, and foxes can be
            affected. Humans are usually only transiently affected.  Figure 165.7  Adult Sarcoptes scabei var. canis.
   1511   1512   1513   1514   1515   1516   1517   1518   1519   1520   1521