Page 1590 - Clinical Small Animal Internal Medicine

1528 Section 13 Diseases of Bone and Joint

dogs led to increased bone remodeling. While markers Osteoporosis is rarely diagnosed in cats and dogs, in part
VetBooks.ir of bone formation (alkaline phosphatase and osteocal­ possibly due to not considering it as a differential diag­
cin) may be increased in cats with hyperthyroidism,
nosis for lameness or bone pain, and the insensitivity of
definitive data on the effect of thyrotoxicosis on bone
are lacking. radiography for its diagnosis. The future use of improved
diagnostic testing such as DEXA and CT may reveal that
Drugs – in humans, ciclosporin and phenobarbital osteoporosis is more common in these species than is
●
have been associated with osteoporosis. currently thought.

Further Reading

Craig LE, Dittmer KE, Thompson KG. Bones and joints. Jones B, Mooney CT. Drugs used in the management of
In: Grant Maxie M, ed. Jubb, Kennedy and Palmer’s thyroid and parathyroid disease. In: Maddison J, Page S,
Pathology of Domestic Animals, 6th edn. St Louis, MO: Church D, eds. Small Animal Clinical Pharmacology,
Elsevier, 2016, pp. 160–63. 2nd edn. Edinburgh: WB Saunders, 2008, pp. 498–508.
Dittmer KE, Thompson KG. Vitamin D metabolism Mellanby RJ. Beyond the skeleton: the role of vitamin D
and rickets in domestic animals: a review. Vet Pathol in companion animal health. J Small Anim Pract
2011; 48: 389–407. 2016; 57: 175–80.
Hardcastle MR, Dittmer KE. Fibroblast growth factor 23: Segev G, Meltzer H, Shipov A. Does secondary renal
a new dimension to diseases of calcium‐phosphorus osteopathy exist in companion animals? Vet Clin North
metabolism. Vet Pathol 2015; 52: 770–84. Am Small Anim Pract 2016; 46: 1151–62.