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References  133

             (if the CT imaging is not sufficient to establish a diagnosis). Such diagnostics may include ultra-
             sound (for muscle pathology), fine‐needle aspirate, biopsy, or arthrocentesis to differentiate spe-
             cific disease processes causing increased SUV, such as infection, inflammation, or cancer.
               All nuclear medicine studies require special imaging equipment and appropriate nuclear medi-
             cine facilities. Disadvantages of PET/CT imaging include extremely limited availability, long scan
             times, ionizing radiation, need for general anesthesia, and cost. Currently, this imaging modality is
             mostly limited to university and tertiary referral hospitals.



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