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               Cardiopulmonary Resuscitation

               Nathan Peterson, DVM, DACVECC

               VCA West Los Angeles Animal Hospital, Los Angeles, CA, USA


               Approximately 330,000 people die of acute cardiac arrest   patients will exhibit loss of consciousness, absence of
               in  the United States  annually.  The incidence  of unex-  spontaneous ventilation, absence of heart sounds during
               pected cardiopulmonary arrest (CPA) in veterinary   auscultation, and absence of palpable pulses.
               patients is currently unknown. What is known is that   The importance of recognizing CPA quickly is under-
               survival rates for dogs and cats that receive cardiopul-  scored when the hemodynamic impact is considered.
               monary  resuscitation  (CPR)  range  from  2.6%  to  25%.   Following the onset of CPA, the aortic blood pressure
               The reported survival rates for people experiencing CPR   drops precipitously, with intrathoracic aortic pressure
               are equally dismal, with overall survival rates following   dropping from a normal of approximately 120 mmHg to
               in‐hospital arrest ranging from 3% to 27%. The reason   20 mmHg within 30 seconds. Additionally, carotid blood
               for the wide range in outcomes is due in part to the vari-  flow decreases from an average of 190 mL/min to 15 mL/
               ance in the nature or cause of cardiopulmonary arrest.   min within 15 seconds and to 0 mL/min within four min-
               What the literature generally agrees on is that the chance   utes. Coronary perfusion pressure likewise drops from
               of a patient surviving to discharge after CPA is small. The   60 mmHg to 15 mmHg within 15 seconds and to 0 mmHg
               likelihood of survival increases if CPA was due to an   within four minutes.
               anesthetic event rather than the culmination of a chronic   Although the underlying cause of CPA may not be
               or traumatic disease process. While the survival statis-  immediately apparent to the clinician,  the nature or
               tics are dismal, the long‐term neurologic outcomes of   cause of the arrest can have an impact on the expected
               patients surviving CPA are generally good to excellent,   outcome and should be ascertained as soon as possible.
               making CPR a worthy endeavor.                      If a patient is known to have suffered respiratory arrest
                 In 2010, veterinary‐specific CPR guidelines were devel-  prior to cardiac arrest, the likelihood of resuscitation
               oped using an evidence‐based approach modeled on the   may be diminished due to the continued depletion of
               American Heart Association’s CPR guidelines. The result   oxygen from circulating blood resulting in severe hypox-
               of this effort was the publication of the Reassessment   emia at the onset of cardiac failure and institution of
               Campaign on Veterinary Resuscitation (RECOVER) in   CPR. Conversely, if an animal suffers sudden cardiac
               2011. The RECOVER initiative (http://onlinelibrary.wiley.  arrest, the blood oxygen content would be expected to be
               com/doi/10.1111/vec.2012.22.issue‐s1/issuetoc) has pro-  high at the onset of CPA and subsequent CPR, possibly
               vided veterinarians for the first time with evidence‐based   making successful resuscitation more likely than in the
               clinical guidelines for performance of CPR.        previous instance.
                 The progression from severe illness to cardiopulmo-
               nary arrest in the veterinary patient is complex. Diseases
               that can lead to CPA in veterinary medicine include but     Principles of CPR
               are not limited to sepsis, pulmonary failure, neoplasia,
               polytrauma, head trauma, and cardiac failure. Although   Cardiopulmonary resuscitation is intended to provide
               not all animals progressing toward CPA follow the same   blood flow to the heart and brain, preserving them until
               clinical course, some physical exam findings that may   return of spontaneous circulation (ROSC) is achieved.
               indicate impending CPA include decreasing level of con-  Subsequently, the quality of chest compressions is of
               sciousness, hypothermia, bradycardia, hypotension, and   the utmost importance, since this is the mechanism by
               changes in respiratory patterns. Once CPA occurs, all   which circulation is generated. Whatever the   technique,

               Clinical Small Animal Internal Medicine Volume I, First Edition. Edited by David S. Bruyette.
               © 2020 John Wiley & Sons, Inc. Published 2020 by John Wiley & Sons, Inc.
               Companion website: www.wiley.com/go/bruyette/clinical
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