Page 424 - Withrow and MacEwen's Small Animal Clinical Oncology, 6th Edition
P. 424
402 PART IV Specific Malignancies in the Small Animal Patient
202. Serra Varela JC, Pecceu E, Handel I, et al.: Tolerability of a rapid- 222. Lin TY, Fenger J, Murahari S, et al.: AR-42, a novel HDAC inhibi-
escalation vinblastine-prednisolone protocol in dogs with mast cell tor, exhibits biologic activity against malignant mast cell lines via
tumours, Vet Med Sci 2:266–280, 2016. down-regulation of constitutively activated Kit, Blood 115:4217–
VetBooks.ir 203. Ma Y, Longley BJ, Wang X, et al.: Clustering of activating muta- 223. Nagamine MK, Sanches DS, Pinello KC, et al.: In vitro inhibitory
4225, 2010.
tions in c-KIT’s juxtamembrane coding region of canine mast cell
neoplasms, J Invest Dermatol 112:165–170, 1999.
204. Liao AT, Chien MB, Shenoy N, et al.: Inhibition of constitutively effect of trichostatin A on canine grade 3 mast cell tumor, Vet Res
Commun 35:391–399, 2011.
active forms of mutant kit by multitargeted indolinone tyrosine 224. Lin TY, Bear M, Du Z, et al.: The novel HSP90 inhibitor STA-
kinase inhibitors, Blood 100:585–593, 2002. 9090 exhibits activity against Kit-dependent and -independent
205. Pryer NK, Lee LB, Zadovaskaya R, et al.: Proof of target for malignant mast cell tumors, Exp Hematol 36:1266–1277, 2008.
SU11654: inhibition of KIT phosphorylation in canine mast cell 225. London CA, Bear MD, McCleese J, et al.: Phase I evaluation of
tumors, Clin Cancer Res 9:5729–5734, 2003. STA-1474, a prodrug of the novel HSP90 inhibitor ganetespib, in
206. London CA, Malpas PB, Wood-Follis SL, et al.: Multi-center, pla- dogs with spontaneous cancer, PLoS One 6:e27018, 2011.
cebo-controlled, double-blind, randomized study of oral toceranib 226. Pinello KC, Nagamine M, Silva TC, et al.: In vitro chemosensitiv-
phosphate (SU11654), a receptor tyrosine kinase inhibitor, for the ity of canine mast cell tumors grades II and III to all-trans-retinoic
treatment of dogs with recurrent (either local or distant) mast cell acid (ATRA), Vet Res Commun 33:581–588, 2009.
tumor following surgical excision, Clin Cancer Res 15:3856–3865, 227. Ohashi E, Miyajima N, Nakagawa T, et al.: Retinoids induce
2009. growth inhibition and apoptosis in mast cell tumor cell lines, J Vet
207. Weishaar KM, Ehrhart EJ, Avery AC, et al.: c-Kit mutation and Med Sci 68:797–802, 2006.
localization status as response predictors in mast cell tumors in dogs 228. Miyajima N, Watanabe M, Ohashi E, et al.: Relationship between
treated with prednisone and toceranib or vinblastine, J Vet Intern retinoic acid receptor alpha gene expression and growth-inhibitory
Med 32:394–405, 2018. effect of all-trans retinoic acid on canine tumor cells, J Vet Intern
208. Tjostheim SS, Stepien RL, Markovic LE, et al.: Effects of toceranib Med 20:348–354, 2006.
phosphate on systolic blood pressure and proteinuria in dogs, J Vet 229. Elders RC, Baines SJ, Catchpole B: Susceptibility of the C2 canine
Intern Med 30:951–957, 2016. mastocytoma cell line to the effects of tumor necrosis factor-related
209. London C, Mathie T, Stingle N, et al.: Preliminary evidence for apoptosis-inducing ligand (TRAIL), Vet Immunol Immunopathol
biologic activity of toceranib phosphate (Palladia((R))) in solid 130:11–16, 2009.
tumours, Vet Comp Oncol 10:194–205, 2012. 230. Peter B, Gleixner KV, Cerny-Reiterer S, et al.: Polo-like kinase-1
210. Hahn KA, Ogilvie G, Rusk T, et al.: Masitinib is safe and effec- as a novel target in neoplastic mast cells: demonstration of growth-
tive for the treatment of canine mast cell tumors, J Vet Intern Med inhibitory effects of small interfering RNA and the Polo-like
22:1301–1309, 2008. kinase-1 targeting drug BI 2536, Haematologica 96:672–680,
211. Hahn KA, Legendre AM, Shaw NG, et al.: Evaluation of 12- and 2011.
24-month survival rates after treatment with masitinib in dogs with 231. London CA, Gardner HL, Rippy S, et al.: KTN0158, a human-
nonresectable mast cell tumors, Am J Vet Res 71:1354–1361, 2010. ized anti-KIT monoclonal antibody, demonstrates biologic activity
212. Isotani M, Ishida N, Tominaga M, et al.: Effect of tyrosine kinase against both normal and malignant canine mast cells, Clin Cancer
inhibition by imatinib mesylate on mast cell tumors in dogs, J Vet Res 23:2565–2574, 2017.
Intern Med 22:985–988, 2008. 232. Macy DW: Canine and feline mast cell tumors: biologic behav-
213. Marconato L, Bettini G, Giacoboni C, et al.: Clinicopathological ior, diagnosis, and therapy, Sem Vet Med Surg (Sm An) 1:72–83,
features and outcome for dogs with mast cell tumors and bone mar- 1986.
row involvement, J Vet Intern Med 22:1001–1007, 2008. 233. Kenyon AJ, Ramos L, Michaels EB: Histamine-induced suppressor
214. Yamada O, Kobayashi M, Sugisaki O, et al.: Imatinib elicited a macrophage inhibits fibroblast growth and wound healing, Am J
favorable response in a dog with a mast cell tumor carrying a c-kit Vet Res 44:2164–2166, 1983.
c.1523A>T mutation via suppression of constitutive KIT activa- 234. Huttunen M, Hyttinen M, Nilsson G, et al.: Inhibition of kerati-
tion, Vet Immunol Immunopathol 142:101–106, 2011. nocyte growth in cell culture and whole skin culture by mast cell
215. Bavcar S, de Vos J, Kessler M, et al.: Combination toceranib and mediators, Exp Dermatol 10:184–192, 2001.
lomustine shows frequent high grade toxicities when used for treat- 235. Saar C, Opitz M, Lange W, et al.: Mastzellenreitkulose bei katzen,
ment of non-resectable or recurrent mast cell tumours in dogs: a Berl Munch Tierarztl Wochenschr 82:438–444, 1969.
European multicentre study, Vet J 224:1–6, 2017. 236. Hadzijusufovic E, Peter B, Rebuzzi L, et al.: Growth-inhibitory
216. Burton JH, Venable RO, Vail DM, et al.: Pulse-administered toc- effects of four tyrosine kinase inhibitors on neoplastic feline mast
eranib phosphate plus lomustine for treatment of unresectable mast cells exhibiting a Kit exon 8 ITD mutation, Vet Immunol Immuno-
cell tumors in dogs, J Vet Intern Med 29:1098–1104, 2015. pathol 132:243–250, 2009.
217. Pan X, Tsimbas K, Kurzman ID, et al.: Safety evaluation of combi- 237. Isotani M, Tamura K, Yagihara H, et al.: Identification of a c-kit
nation CCNU and continuous toceranib phosphate (Palladia((R))) exon 8 internal tandem duplication in a feline mast cell tumor case
in tumour-bearing dogs: a phase I dose-finding study, Vet Comp and its favorable response to the tyrosine kinase inhibitor imatinib
Oncol 14:202–209, 2016. mesylate, Vet Immunol Immunopathol 114:168–172, 2006.
218. Robat C, London C, Bunting L, et al.: Safety evaluation of combi- 238. Isotani M, Yamada O, Lachowicz JL, et al.: Mutations in the fifth
nation vinblastine and toceranib phosphate (Palladia(R)) in dogs: a immunoglobulin-like domain of kit are common and potentially
phase I dose-finding study, Vet Comp Oncol 10:174–183, 2012. sensitive to imatinib mesylate in feline mast cell tumours, Br J Hae-
219. Carlsten KS, London CA, Haney S, et al.: Multicenter prospective matol 148:144–153, 2009.
trial of hypofractionated radiation treatment, toceranib, and pred- 239. Chastain CB, Turk MA, O’Brien D: Benign cutaneous mastocyto-
nisone for measurable canine mast cell tumors, J Vet Intern Med mas in two litters of Siamese kittens, J Am Vet Med Assoc 193:959–
26:135–141, 2012. 960, 1988.
220. Keller A, Wingelhofer B, Peter B, et al.: The JAK2/STAT5 signaling 240. Mohr FC, Dunston SK: Culture and initial characterization of the
pathway as a potential therapeutic target in canine mastocytoma, secretory response of neoplastic cat mast cells, Am J Vet Res 53:820–
Vet Comp Oncol 16:55–68, 2018. 828, 1992.
221. Kisseberth WC, Murahari S, London CA, et al.: Evaluation of the 241. Antognoni MT, Spaterna A, Lepri E, et al.: Characteristic clinical,
effects of histone deacetylase inhibitors on cells from canine cancer haematological and histopathological findings in feline mastocy-
cell lines, Am J Vet Res 69:938–945, 2008. toma, Vet Res Commun 27(suppl 1):727–730, 2003.