Page 107 - Small Animal Clinical Nutrition 5th Edition
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108        Small Animal Clinical Nutrition



                    Table 6-1. Mineral functions and effects of deficiencies and excesses.
        VetBooks.ir  Mineral   Function                     Deficiency                 Excess

                               Constituent of bone and teeth,
                                                                                       Decreased feed efficiency and feed intake,
                    Calcium
                                                            Decreased growth, decreased
                               blood clotting, muscle function, nerve
                                                                                       junctions. Increased calcium intake is a risk
                                                            mineralization, lameness,
                               transmission, membrane permeability  appetite, decreased bone   nephrosis, lameness, enlarged costochondral
                                                            spontaneous fractures, loose teeth,   factor for calcium-containing urinary
                                                            tetany, convulsions, rickets   precipitates; however, moderate- to high-
                                                            (osteomalacia in adults)   calcium levels may be protective against
                                                                                       calcium oxalate precipitates. Calcium in
                                                                                       meals may bind with oxalate in the gut
                                                                                       decreasing the risk.
                    Phosphorus  Constituent of bone and teeth,   Depraved appetite, pica,  Bone loss, uroliths, decreased weight gain,
                               muscle formation, fat, carbohydrate   decreased feed efficiency,   decreased feed intake, calcification of soft
                               and protein metabolism, phospholipids  decreased growth, dull coat,   tissues, secondary hyperparathyroidism
                               and energy production, reproduction  decreased fertility, spontaneous
                                                            fractures, rickets
                    Potassium  Muscle contraction, transmission of  Anorexia, decreased growth,    Rare. Paresis, bradycardia
                               nerve impulses, acid-base balance,   lethargy, locomotive problems,
                               osmotic balance, enzyme cofactor   hypokalemia, heart and kidney
                               (energy transfer)            lesions, emaciation
                    Sodium and   Osmotic pressure, acid-base balance,   Inability to maintain water balance,   Occurs only if there is inadequate good-
                    chloride   transmission of nerve impulses,   decreased growth, anorexia,   quality water available. Thirst, pruritus,
                               nutrient uptake, waste excretion,   fatigue, exhaustion, hair loss  constipation, seizures and death
                               water metabolism
                    Magnesium  Component of bone and intracellular   Muscle weakness, hyperirritability,   Uroliths, flaccid paralysis
                               fluids, neuromuscular transmission,   convulsions, anorexia, vomiting,
                               active component of several enzymes,  decreased mineralization of bone,
                               carbohydrate and lipid metabolism  decreased body weight,
                                                            calcification of aorta
                    Iron       Enzyme constituent, activation of   Anemia, rough coat, listlessness,   Anorexia, weight loss, decreased serum
                               O (oxidases and oxygenases),   decreased growth         albumin concentrations, hepatic dysfunction,
                                2
                               oxygen transport (hemoglobin,                           hemosiderosis
                               myoglobin)
                    Zinc       Constituent or activator of 200 known  Anorexia, decreased growth,     Relatively nontoxic. Reported cases of zinc
                               enzymes (nucleic acid metabolism,   alopecia, parakeratosis, impaired   toxicity from consumption of die-cast zinc
                               protein synthesis, carbohydrate   reproduction, vomiting, hair   nuts or pennies
                               metabolism), skin and wound healing,   depigmentation, conjunctivitis
                               immune response, fetal development,
                               growth rate
                    Copper     Component of several enzymes   Anemia, decreased growth, hair   Hepatitis, increased liver enzyme activity
                               (oxidases), catalyst in hemoglobin   depigmentation, bone lesions,
                               formation, cardiac function, cellular   neuromuscular disorders,
                               respiration, connective tissue   reproductive failure
                               development, pigmentation, bone
                               formation, myelin formation, immune
                               function
                    Manganese  Component and activator of enzymes   Impaired reproduction, fatty liver,   Relatively nontoxic
                               (glycosyl transferases), lipid and   crooked legs, decreased growth
                               carbohydrate metabolism, bone
                               development (organic matrix),
                               reproduction, cell membrane
                               integrity (mitochondria)
                    Selenium   Constituent of glutathione peroxidase   Muscular dystrophy, reproductive   Vomiting, spasms, staggered gait, salivation,
                               and iodothyronine 5’-deiodinase,   failure, decreased feed intake,   decreased appetite, dyspnea, oral malodor,
                               immune function, reproduction  subcutaneous edema, renal  nail loss
                                                            mineralization
                    Iodine     Constituent of thyroxine and   Goiter, fetal resorption, rough coat,   Similar to those caused by deficiency.
                               triiodothyronine             enlarged thyroid glands, alopecia,   Decreased appetite, listlessness, rough coat,
                                                            apathy, myxedema, lethargy  decreased immunity, decreased weight gain,
                                                                                       goiter, fever
                    Boron      Regulates parathyroid hormone,   Decreased growth, decreased   Similar to those caused by deficiency
                               influences metabolism of calcium,   hematocrit, hemoglobin and
                               phosphorus, magnesium and    alkaline phosphatase values
                               cholecalciferol
                    Chromium   Potentiates insulin action, therefore   Impaired glucose tolerance,   Trivalent form less toxic than hexavalent.
                               improves glucose tolerance   increased serum triglyceride and   Dermatitis, respiratory irritation, lung cancer
                                                            cholesterol concentrations
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