Page 900 - Small Animal Clinical Nutrition 5th Edition
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932        Small Animal Clinical Nutrition




        VetBooks.ir  Table 46-7. Clinical and diagnostic findings associated with the most common feline uroliths.*  Purine (urate)
                    Parameters
                                           Struvite
                                                                       Calcium oxalate
                    Breed predisposition
                                           Chartreux
                                                                       British shorthair
                                           Domestic longhair           Burmese                 Siamese
                                           Domestic shorthair          Exotic shorthair
                                           Foreign shorthair           Foreign shorthair
                                           Himalayan                   Havana brown
                                           Manx                        Himalayan
                                           Oriental shorthair          Persian
                                           Ragdoll                     Ragdoll
                                           Siamese                     Scottish fold
                                                                       Domestic shorthair
                    Gender predisposition  Female >male                Male >female            Neutered >intact
                                           Neutered >intact
                    Common age (years)     Younger (<7 years)          Middle-aged to older    Young (if associated with
                                                                       (>7 years)              portosystemic shunt)
                    Serum biochemistries   Normal                      Hypercalcemia           Normal (idiopathic)
                                                                       Acidemia (decreased TCO )  Evidence of hepatic disease
                                                                                         2
                                                                                               (low urea nitrogen,
                                                                                               increased ammonia)
                    Urinary pH**           Slightly acidic (>6.5) or alkaline  Acidic to neutral  Acidic to neutral
                    Bacteria               Usually sterile             Usually sterile         Usually sterile
                                           Occasionally associated with   May be present in cats with   May be present in cats with
                                           urease-producing bacteria   infection secondary to   infection secondary to
                                                                       uroliths                uroliths
                    Typical crystals       Colorless, coffin-lid prisms,   Monohydrate–oval,   Spherical, tan in color
                                           sometimes shaped like squares  dumbbell shaped      May be green/brown
                                                                       Dihydrate-squares with  Thorn apple appearance
                                                                       diagonal lines
                    Radiopacity            1+ to 4+                    3+ to 4+                0 to 2+
                    Radiographic appearance  Rough or smooth, round or   Rough or smooth, usually   Smooth, occasionally irregular
                                           faceted, sometimes disk-shaped  small, occasionally jackstone
                                                                       shaped

                    *Adapted from Osborne CA, Kruger JM, Lulich JP, et al. Disorders of the feline lower urinary tract. In: Osborne CA, Finco DR, eds. Canine
                    and Feline Nephrology and Urology. Baltimore, MD: Williams & Wilkins 1995; 651.
                    **Concomitant infection with urease-producing bacteria may cause alkaline urine in cats with uroliths.



                                                                               b
                                                                      pH meters have become available and are more accurate for
                   Table 46-8. Possible risk factors for urinary tract infection in cats.  measuring urinary pH than reagent strips (Heuter et al, 1998;
                                                                      Raskin et al, 2002; Johnson et al, 2007). These instruments
                   Age (≥10 years)
                   Female gender                                      can be used in veterinary hospitals or by pet owners at home.
                   Urinary tract procedures                           A study in cats revealed that portable pH meters were more
                      Urethral catheterization
                      Perineal urethrostomy                           accurate than pH paper or reagent test strips for measuring
                   Urolithiasis                                       urinary pH in healthy cats (Raskin et al, 2002). Another study
                   Systemic diseases                                  of hospitalized dogs compared hand-held pH meters, pH pa-
                      Chronic kidney disease
                      Hyperthyroidism                                 per and reagent strips with a bench top pH meter, considered
                      Diabetes mellitus                               the gold standard for measuring pH. Results revealed that pH
                                                                      paper and reagent strips had poor to moderate agreement
                                                                      with the reference method, whereas, hand-held pH meters
                  roughly from 5.0 (orange) to 9.0 (blue). According to most  had nearly perfect agreement (Johnson et al, 2007). Based on
                  manufacturers, pH values measured with indicator paper are  these studies, a portable or bench top pH meter should be
                  only accurate to within 0.5 pH units. For best results, indicator  used when accurate urinary pH measurements are crucial for
                  squares on reagent strips should be compared with the manu-  diagnosis or treatment.
                  facturer’s color standards in well-illuminated areas, as directed
                  by product instructions. Urine reagent strips may be used to  Urine Culture
                  estimate pH for routine urinalysis; however, they should not be  Urine culture should be done in all cats with lower urinary tract
                  relied on when accurate pH measurements are needed for diag-  signs or in asymptomatic cats when there is increased risk of
                  nosis, prevention and management of disease (Johnson et al,  UTI (Table 46-8). Quantitative bacterial culture of urine col-
                  2007).                                              lected by cystocentesis is the gold standard for diagnosis of
                    Relatively inexpensive microprocessor-based, pocket-sized  UTI. For most accurate results, urine should be cultured with-
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