Page 922 - Small Animal Clinical Nutrition 5th Edition
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954        Small Animal Clinical Nutrition



                    Table 46-19. Comparison of key nutritional factors in selected commercial veterinary therapeutic foods for reducing the recurrence of
        VetBooks.ir  Moist foods**                  Mg (%)   P (%)  Ca (%)  Protein (%)  Na (%)  Urinary pH Total omega 3 (%)
                    feline idiopathic cystitis, struvite disease (uroliths or urethral plugs) and/or calcium oxalate uroliths in cats.*

                    Recommended levels
                    Hill’s Prescription Diet c/d Multicare   0.07-0.14  0.5-0.9  0.6-1.0  32-45  0.3-0.6  6.2-6.4  0.35-1.0
                     with Chicken Feline             0.052   0.68    0.72     43.8     0.32     6.35        0.96
                    Hill’s Prescription Diet c/d Multicare
                     with Seafood Feline             0.054   0.71    0.62     44.8     0.33     6.4         0.62
                    Medi-Cal Urinary SO               na     1.20    1.20     43.5     1.1      6.4         na
                    Purina Veterinary Diets UR Urinary St/Ox
                     Feline Formula                  0.07    0.97    0.96     50.6     0.62    6.0-6.4      na
                    Royal Canin Veterinary Diet Urinary SO in gel  0.10  1.36  1.02  41.3  1.02  6.0-6.3    na
                    Dry foods                       Mg (%)   P (%)  Ca (%)  Protein (%)  Na (%)  Urinary pH Total omega 3 (%)
                    Recommended levels             0.07-0.14  0.5-0.9  0.6-1.0  32-45  0.3-0.6  6.2-6.4   0.35-1.0
                    Hill’s Prescription Diet c/d Multicare Feline  0.06  0.65  0.74  36.1  0.35  6.3        0.65
                    Hill’s Prescription Diet c/d Multicare
                     with Chicken Feline             0.06    0.65    0.76     34.6     0.33     6.3         0.64
                    Purina Veterinary Diets UR Urinary St/Ox
                     Feline Formula                  0.07    1.08     1.1     44.9     1.17    6.0-6.4      na
                    Key: Mg = magnesium, P = phosphorus, Ca = calcium, Na = sodium, total omega 3 = total omega-3 fatty acids, na = not available from
                    manufacturer.
                    *Nutrients expressed on a dry matter basis unless otherwise stated.
                    **In general, it is recommended that moist foods be fed to cats with lower urinary tract disorders, especially those with feline idiopathic
                    cystitis or calcium oxalate uroliths.



                                                                      Fiber
                    Table 46-20. Descriptions of grades used to classify evidence
                    supporting treatments for cats with lower urinary tract diseases.*  The role of dietary fiber has not been carefully evaluated in cats
                                                                      with lower urinary tract disorders. In an epidemiologic study of
                    Grade  Description of evidence                    cats with uroliths, those fed high-fiber foods (0.71 to 11.57
                    I      At least one properly designed, randomized, controlled
                           clinical study performed in patients of the target  g/100 kcal) were 2.12 times more likely to develop struvite
                           species                                    uroliths than cats fed low-fiber foods (0.06 to 0.30 g/100 kcal)
                    II     Evidence from properly designed, randomized, con-  (Lekcharoensuk et al, 2001a). In the same study there was no
                           trolled studies in animals of the target species with
                           spontaneous disease in a laboratory or research ani-  association between dietary fiber and development of calcium
                           mal colony setting                         oxalate uroliths. Dietary fiber may bind calcium in the small
                    III    Appropriately controlled studies without randomization  intestine, preventing its absorption.There are anecdotal reports
                           Appropriately designed case-control epidemiologic
                           studies                                    that feeding foods with increased fiber helps control hypercal-
                           Studies using models of disease or simulations in the  cemia in cats with concomitant calcium oxalate uroliths
                           target species                             (McClain et al, 1999).
                           Dramatic results from uncontrolled studies
                           Case series
                    IV     Studies conducted in other species
                           Reports of expert committees
                           Descriptive studies                         FEEDING PLANS
                           Case reports
                           Pathophysiologic justification/rationale   Successful management of cats with various lower urinary tract
                           Opinions of respected experts              diseases requires a multifaceted approach and effective commu-
                                                                      nication between health care team members and owners. Nu-
                    *Adapted from Roudebush P, Allen TA, Dodd CE, et al.
                    Application of evidence-based medicine to veterinary clinical  tritional management plays a key role in the treatment of
                    nutrition. Journal of the American Veterinary Medical Association  patients with FIC, struvite disease (uroliths and urethral plugs)
                    2004; 224: 1765-1771.
                                                                      and calcium oxalate uroliths. Environmental enrichment (e.g.,
                                                                      stress reduction, litter box management) also should be imple-
                                                                      mented in patients with FIC and may be helpful for cats with
                                                                      other lower urinary tract disorders.For cats with persistent clin-
                  quent hypercalciuria and increased risk for oxalate uroliths.The  ical signs, especially periuria, behavioral modification may also
                  minimum recommended allowance for vitamin D for adult cats  be needed to correcting the underlying medical disorder. Fi-
                  is 280 IU/kg food (DM; for a food with 4 kcal ME/g DM)  nally, other treatments such as pain management may be need-
                  (NRC, 2006).However,cats at risk for calcium oxalate urolithi-  ed for some cats, especially during acute episodes.
                  asis and those with hypercalcemia associated with calcium  Feeding plans for cats with various lower urinary tract dis-
                  oxalate urolithiasis should be fed foods that do not exceed 2,000  eases continue the iterative process and include the following
                  IU/kg of food. Dietary supplements containing vitamin D  steps: 1) assess and select the food, 2) assess and determine the
                  should not be fed to at-risk cats.                  feeding method and 3) reassess and modify the feeding plan, as
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