Page 779 - Small Animal Clinical Nutrition 5th Edition
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Chronic Kidney Disease   807


                  Progress Notes                       Table 1. Selected serum biochemistry values from a cat with generalized weakness.
        VetBooks.ir  An intravenous catheter was inserted in the  Parameters  Day 1  Day 2  Day 3  Day 4  Day 6  Day 25  Reference
                  cat’s jugular vein and 20 ml of lactated
                                                                                                               values
                  Ringer’s solution was administered per hour
                                                                                                 ND
                                                                                          ND
                                                                                                                8-15
                                                                      9.9
                                                                                                        ND
                                                                            6.7
                                                                                  ND
                                                       Hemoglobin (g/dl)
                  during the first eight hours. After eight  Hematocrit (%)  31  20.3  ND  ND    ND     ND      30-45
                  hours, the rate was reduced to 12 ml/hour.  Total protein (g/dl)  7.9  7.1  6.1  6.3  6.5  ND  6.1-7.7
                                                       Urea nitrogen (mg/dl) 53  58  47   48     51     36      15-25
                  Sixteen mEq of potassium chloride were  Creatinine (mg/dl)  3.0  3.1  2.0  1.9  2.1   2.3    0.8-1.8
                  added to each liter of lactated Ringer’s solu-  Sodium (mmol/l)  165  167  160  158  153  152  140-157
                  tion to produce a final potassium concentra-  Potassium (mmol/l) 3.0  3.4  4.2  5.5  4.6  5.2  3.8-5.3
                                                       Chloride (mmol/l)  137  134  124  122     116    118    115-128
                  tion of 20 mEq/l. During the first day of  Total CO (mmol/l)  11  17  23  29   28     23      18-23
                                                             2
                  hospitalization, 4 mEq of potassium glu-
                                 a
                  conate gel (Tumil-K ) were administered per  Key: ND = not done.
                  os every 12 hours. Water was offered free
                  choice. Body weight was measured daily using the same pediatric scale, and urine output was estimated by weighing the litter box
                  before and after voiding.
                    The cat’s weakness was noticeably improved by Day 2.The cat’s resting energy requirement (RER) was calculated at its estimat-
                  ed ideal body weight of 3.5 kg (RER at 3.5 kg = 175 kcal [732 kJ]). The cat was offered small quantities of dry and moist forms of
                  a commercial food for mature adult cats with controlled amounts of protein and phosphorus, every three to four hours.The cat was
                  consuming sufficient food to meet its RER by Day 4.
                    The azotemia, hypokalemia, acidosis and muscle strength progressively improved over the next three days (Table 1). Six days after
                  initial hospitalization, the patient was discharged to the owner’s care with instructions to gradually transition to feeding a dry vet-
                                          b
                  erinary therapeutic renal food and to administer 4 mEq potassium gluconate gel every 12 hours. The quantity of food was
                  increased to a daily energy requirement of 1.4 x RER.
                    The owner reported that the cat was bright, alert, active and eating well with normal muscle strength 25 days after initial exam-
                  ination. Physical examination was normal except the patient was still underweight (body weight 2.8 kg, BCS 2/5) and the kidneys
                  were still palpably small and irregular. Results of a serum biochemistry profile included mild azotemia, normal serum electrolyte
                  concentrations and normal acid-base status (Table 1). Oral potassium gluconate was discontinued and the dry veterinary therapeu-
                  tic renal food was continued. The owners asked about purchasing moist food from the grocery store to add to the dry veterinary
                  therapeutic renal food. Because most grocery brand foods contain excessive phosphorus and protein compared with therapeutic
                  renal foods, this was not recommended. Instead, several cans of the veterinary therapeutic renal food were dispensed so the owners
                  could determine if the cat preferred moist food in addition to the dry food.

                  Endnotes
                  a. Daniels Pharmaceuticals Inc., St. Petersburg, FL, USA.
                  b. Prescription Diet k/d Feline. Hill’s Pet Nutrition, Inc., Topeka, KS, USA.

                  Bibliography
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                  American Veterinary Medical Association 1993; 202: 744-751.
                  Dow SW, LeCouteur RA, Fettman MJ, et al. Hypokalemia in cats: 186 cases (1984-1987). Journal of the American Veterinary
                  Medical Association 1989; 194: 1604-1608.
                  Dow SW, LeCouteur RA, Fettman MJ, et al. Potassium depletion in cats: Hypokalemic polymyopathy. Journal of the American
                  Veterinary Medical Association 1987; 191: 1569-1575.
                  Elliott J, Barber PJ. Feline chronic renal failure: Clinical findings in 80 cases diagnosed between 1992 and 1995. Journal of Small
                  Animal Practice 1998; 39: 78-85.
                  Theisen SK, DiBartola SP, Radin J, et al. Muscle potassium content and potassium gluconate supplementation in normokalemic
                  cats with naturally occurring chronic renal failure. Journal of Veterinary Internal Medicine 1997; 11: 212-217.
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