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intubation and mechanical ventilation may be
                                                required.
                                             2. Monitor respiratory status, because respiratory
                                                compromise and cerebral edema may occur 24 hours
                                                after the incident.
                                             3. Monitor for aspiration pneumonia.
                                             4. Monitor neurological status closely; if spontaneous
                                                purposeful movement and normal brainstem function
                                                are not apparent 24 hours after the event, the child
                                                most likely has sustained severe neurological deficits.
                                             5. Teach parents to provide adequate supervision of
                                                infants and small children around water to prevent
                                                accidents.
                    VI. Reye’s Syndrome
                                A. Description
                                             1. Reye’s syndrome is an acute encephalopathy that
                                                follows a viral illness and is characterized
                                                pathologically by cerebral edema and fatty changes in
                                                the liver; diagnosis is made by laboratory studies and
                                                liver biopsy.
                                             2. The exact cause is unclear; it most commonly follows a
                                                viral illness such as influenza or varicella.

                                                      3. Administration of aspirin and aspirin-

                                                containing products is not recommended for children
                                                with a febrile illness or children with varicella or
                                                influenza because of its association with Reye’s
                                                syndrome.
                                             4. Acetaminophen or ibuprofen are considered the
                                                medications of choice.
                                             5. Early diagnosis and aggressive treatment are
                                                important; the goal of treatment is to maintain
                                                effective cerebral perfusion and control increasing
                                                ICP.
                                B. Assessment
                                             1. History of systemic viral illness 4 to 7 days before the
                                                onset of symptoms
                                             2. Fever
                                             3. Nausea and vomiting

                                                      4. Signs of altered hepatic function such as

                                                lethargy

                                                      5. Progressive neurological deterioration

                                             6. Increased blood ammonia levels

                                        C. Interventions




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