Page 1215 - Saunders Comprehensive Review For NCLEX-RN
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part, which may result in further tissue damage.
                                             4. The rewarming process may be painful; analgesics
                                                may be necessary.
                                             5. Avoid compression of the injured tissues and apply
                                                only loose and nonadherent sterile dressings.
                                             6. Monitor for signs of compartment syndrome.
                                             7. Tetanus prophylaxis is necessary, and topical and
                                                systemic antibiotics may be prescribed.
                                             8. Debridement of necrotic tissue may be needed;
                                                amputation may be necessary if gangrene develops.
                    XIII. Actinic Keratoses
                                A. Actinic keratoses are caused by chronic exposure to the sun and
                                   appear as rough, scaly, red, or brown lesions that are usually
                                   found on the face, scalp, arms, and backs of the hands.
                                B. Lesions are considered premalignant, and there is risk for slow
                                   progression to squamous cell carcinoma.
                                C. Treatment includes medications, excision, cryotherapy, curettage,
                                   and laser therapy.
                                D. See Chapter 43 for information on medications to treat this
                                   disorder.
                            XIV. Skin Cancer


                                A. Description
                                             1. Skin cancer is a malignant lesion of the skin, which
                                                may or may not metastasize.
                                             2. Overexposure to the sun is a primary cause; other
                                                causes and conditions that place the individual at risk
                                                include chronic skin damage from repeated injury
                                                and irritation such as tanning and use of tanning
                                                beds, genetic predisposition, ionizing radiation, light-
                                                skinned race, age older than 60 years, an outdoor
                                                occupation, and exposure to chemical carcinogens.
                                             3. Diagnosis is confirmed by skin biopsy.
                                B. Types
                                             1. Basal cell: Basal cell cancer arises from the basal cells
                                                contained in the epidermis; metastasis is rare, but
                                                underlying tissue destruction can progress to organ
                                                tissue.
                                             2. Squamous cell: Squamous cell cancer is a tumor of the
                                                epidermal keratinocytes and can infiltrate
                                                surrounding structures and metastasize to lymph
                                                nodes.
                                             3. Melanoma: Melanoma may occur any place on the
                                                body, especially where birthmarks or new moles are
                                                apparent; it is highly metastatic to the brain, lungs,
                                                bone, and liver, with survival depending on early
                                                diagnosis and treatment.
                                C. Assessment (see Box 42-2)


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