Page 1366 - Saunders Comprehensive Review For NCLEX-RN

Health Problem: Adult Health: Cancer: Cervical/Uterine/Ovarian
Priority Concepts: Cellular Regulation; Clinical Judgment
Reference: Hodgson, Kizior (2018), p. 1227.

478. Answer: 1

Rationale: Asparaginase is contraindicated if hypersensitivity exists, in
pancreatitis, or if the client has a history of pancreatitis. The medication impairs
pancreatic function, and pancreatic function tests should be performed before
therapy begins and when a week or more has elapsed between dose administrations.
The client needs to be monitored for signs of pancreatitis, which include nausea,
vomiting, and abdominal pain. The conditions noted in options 2, 3, and 4 are not
contraindicated with this medication.
Test-Taking Strategy: Focus on the subject, a contraindication of asparaginase. It
is necessary to know the contraindications associated with this medication. Recalling
that this medication affects pancreatic function will direct you to the correct option.
Level of Cognitive Ability: Analyzing
Client Needs: Physiological Integrity
Integrated Process: Nursing Process—Assessment
Content Area: Pharmacology: Oncology Medications: Hormonal and Enzymes
Health Problem: N/A
Priority Concepts: Cellular Regulation; Clinical Judgment
Reference: Hodgson, Kizior (2018), p. 87.

479. Answer: 3

Rationale: Tamoxifen is an antineoplastic medication that competes with estradiol
for binding to estrogen in tissues containing high concentrations of receptors.
Tamoxifen is used to treat metastatic breast carcinoma in women and men.
Tamoxifen is also effective in delaying the recurrence of cancer following
mastectomy and for preventing breast cancer in those that are at high risk.
Test-Taking Strategy: Note the strategic words, most appropriately. Recalling that
this medication is used for breast cancer will assist you in eliminating options 2 and
4. Note the closed-ended word “only” in option 1 to assist you in eliminating this
option. Also, recall that this medication is used for both prevention and treatment of
breast cancer.
Level of Cognitive Ability: Applying
Client Needs: Physiological Integrity
Integrated Process: Teaching and Learning
Content Area: Pharmacology: Oncology Medications: Selective Estrogen Receptor
Modulators
Health Problem: Adult Health: Cancer: Breast
Priority Concepts: Cellular Regulation; Clinical Judgment
Reference: Lewis et al. (2017), 1217.

480. Answer: 2

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