Page 1472 - Saunders Comprehensive Review For NCLEX-RN
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Priority Concepts: Clinical Judgment; Thermoregulation
                  Reference: Lewis et al. (2017), p. 1169.


                   522. Answer: 3


                  Rationale: Oral doses of levothyroxine should be taken on an empty stomach to
               enhance absorption. Dosing should be done in the morning before breakfast.
                  Test-Taking Strategy: Note that options 1, 2, and 4 are comparable or alike in that
               these options address administering the medication with food.
                  Level of Cognitive Ability: Applying
                  Client Needs: Physiological Integrity
                  Integrated Process: Teaching and Learning
                  Content Area: Pharmacology: Endocrine Medications: Thyroid Hormones
                  Health Problem: Adult Health: Endocrine: Thyroid Disorders
                  Priority Concepts: Client Education; Thermoregulation
                  Reference: Hodgson, Kizior (2018), p. 675.


                   523. Answer: 2


                  Rationale: Excessive doses of levothyroxine can produce signs and symptoms of
               hyperthyroidism. These include tachycardia, chest pain, tremors, nervousness,
               insomnia, hyperthermia, extreme heat intolerance, and sweating. The client should
               be instructed to notify the PHCP if these occur. Options 1, 3, and 4 are signs of
               hypothyroidism.
                  Test-Taking Strategy: Focus on the subject, the need to notify the PHCP. Recall
               the symptoms associated with hypothyroidism, the purpose of administering
               levothyroxine, and the effects of the medication. Options 1, 3, and 4 are symptoms
               related to hypothyroidism.
                  Level of Cognitive Ability: Applying
                  Client Needs: Physiological Integrity
                  Integrated Process: Teaching and Learning
                  Content Area: Pharmacology: Endocrine Medications: Thyroid Hormones
                  Health Problem: Adult Health: Endocrine: Thyroid Disorders
                  Priority Concepts: Client Education; Safety
                  Reference: Lewis et al. (2017), p. 1169.


                   524. Answer: 2


                  Rationale: Pramlintide is used for clients with types 1 and 2 diabetes mellitus who
               use insulin. It is administered subcutaneously before meals to lower blood glucose
               level after meals, leading to less fluctuation during the day and better long-term
               glucose control. Because pramlintide delays gastric emptying, any prescribed oral
               medications should be taken 1 hour before or 2 hours after an injection of
               pramlintide; therefore, instructing the client to take his or her pills 1 hour before or 2
               hours after the injection is correct. Pramlintide should not be taken at the same time
               as other medications. Pramlintide is given immediately before the meal in order to
               control postprandial rise in blood glucose, not necessarily to prevent stomach upset.



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