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decreasing blood volume, and thus decreasing BP.
                                             8. Decreases in blood volume result in increased
                                                antidiuretic hormone release; this promotes an
                                                increase in blood volume and therefore BP.
                                             9. Renin, a potent vasoconstrictor, causes the BP to
                                                increase.
                                           10. Renin converts angiotensinogen to angiotensin I;
                                                angiotensin I is then converted to angiotensin II in the
                                                lungs.
                                           11. Angiotensin II stimulates the release of aldosterone,
                                                which promotes water and sodium retention by the
                                                kidneys; this action increases blood volume and BP.

                                        N. The vascular system

                                             1. Arteries are vessels through which the blood passes
                                                away from the heart to various parts of the body; they
                                                convey highly oxygenated blood from the left side of
                                                heart to the tissues.
                                             2. Arterioles control the blood flow into the capillaries.
                                             3. Capillaries allow the exchange of fluid and nutrients
                                                between the blood and the interstitial spaces.
                                             4. Venules receive blood from the capillary bed and
                                                move blood into the veins.
                                             5. Veins transport deoxygenated blood from the tissues
                                                back to the right heart and then to the lungs for
                                                oxygenation.
                                             6. Valves help return blood to the heart against the force
                                                of gravity.
                                             7. The lymphatics drain the tissues and return the tissue
                                                fluid to the blood.
                    II. Diagnostic Tests and Procedures (refer to Chapter 10 for further information
                       on laboratory reference levels)

                                        A. Cardiac markers

                                             1. Troponin
                                                             a. Troponin is composed of 3 proteins—
                                                                troponin C, cardiac troponin I, and
                                                                cardiac troponin T.
                                                             b. Troponin I especially has a high affinity
                                                                for myocardial injury; it rises within 3
                                                                hours and persists for up to 7 to 10
                                                                days.
                                                             c. Normal values are low, with troponin I
                                                                being less than 0.35 ng/mL (less than
                                                                0.35 mcg/L) and troponin T being less
                                                                than 0.1 ng/mL (less than 0.1 mcg/L);
                                                                thus, any rise can indicate myocardial




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