Page 1771 - Saunders Comprehensive Review For NCLEX-RN

7. Uncontrolled hypertension
8. Recent, prolonged cardiopulmonary resuscitation
9. Known allergy to the product or its preservatives
C. Side and adverse effects
1. Bleeding
2. Dysrhythmias
3. Allergic reactions
D. Interventions
1. Determine aPTT, PT, fibrinogen level, hematocrit, and
platelet count.
2. Monitor vital signs.
3. Assess pulses.
4. Monitor for bleeding and check all excretions for
occult blood.

5. Monitor for neurological changes such as

slurred speech, lethargy, confusion, and hemiparesis.
6. Monitor for hypotension and tachycardia.
7. Avoid injections and venipunctures if possible.
8. Apply direct pressure over a puncture site for 20 to 30
minutes.
9. Handle the client gently and as little as possible when
moving.
10. Instruct the client to use an electric razor for shaving
and to brush teeth gently.

11. Withhold the medication if bleeding develops,

and notify the primary health care provider (PHCP).

12. Antidote: Aminocaproic acid is the antidote.

Bleeding is the primary concern for a client taking an

anticoagulant, thrombolytic, or antiplatelet medication.
III. Antiplatelet Medications (Box 53-4)
A. Description
1. Antiplatelet medications inhibit the aggregation of
platelets in the clotting process, thereby prolonging
the bleeding time.
2. Antiplatelet medications may be used with
anticoagulants.
3. Used in the prophylaxis of long-term complications
following myocardial infarction, coronary
revascularization, stents, and stroke.
4. These medications are contraindicated in those with
bleeding disorders and known sensitivity.

1771