Page 988 - Saunders Comprehensive Review For NCLEX-RN
P. 988

route and is contraindicated in
                                                                children with an allergy to peanuts
                                                                because the medication is prepared in
                                                                a peanut oil solution; it is also
                                                                contraindicated in children with
                                                                glucose-6-phosphate dehydrogenase
                                                                (G6PD) deficiency and should not be
                                                                given with iron.
                                                             e. The function of the renal, hepatic, and
                                                                hematological systems must be
                                                                monitored closely.
                                                             f. Ensure adequate urinary output before
                                                                administering the medication, and
                                                                monitor the output and pH of the
                                                                urine closely during and after therapy.
                                                             g. Provide adequate hydration and
                                                                monitor kidney function for
                                                                nephrotoxicity when the medication is
                                                                given, because the medication is
                                                                excreted via the kidneys.
                                                             h. Follow-up of lead levels needs to be
                                                                done to monitor progress.
                                                             i. Provide instructions to parents about
                                                                safety from lead hazards, medication
                                                                administration, and the need for
                                                                follow-up.
                                                             j. Confirm that the child will be
                                                                discharged to a home without lead
                                                                hazards.

                                B.         Acetaminophen

                                             1. Description
                                                             a. Seriousness of ingestion is determined
                                                                by the amount ingested and the length
                                                                of time before intervention.
                                                             b. Toxic dose is 150 mg/kg or higher in
                                                                children.
                                             2. Assessment
                                                             a. First 2 to 4 hours: Malaise, nausea,
                                                                vomiting, sweating, pallor, weakness
                                                             b. Latent period: 24 to 36 hours; child
                                                                improves
                                                             c. Hepatic involvement: May last 7 days
                                                                and may be permanent; right upper
                                                                quadrant pain, jaundice, confusion,
                                                                stupor, elevated liver enzyme and
                                                                bilirubin levels, prolonged
                                                                prothrombin time


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