Page 988 - Saunders Comprehensive Review For NCLEX-RN
P. 988
route and is contraindicated in
children with an allergy to peanuts
because the medication is prepared in
a peanut oil solution; it is also
contraindicated in children with
glucose-6-phosphate dehydrogenase
(G6PD) deficiency and should not be
given with iron.
e. The function of the renal, hepatic, and
hematological systems must be
monitored closely.
f. Ensure adequate urinary output before
administering the medication, and
monitor the output and pH of the
urine closely during and after therapy.
g. Provide adequate hydration and
monitor kidney function for
nephrotoxicity when the medication is
given, because the medication is
excreted via the kidneys.
h. Follow-up of lead levels needs to be
done to monitor progress.
i. Provide instructions to parents about
safety from lead hazards, medication
administration, and the need for
follow-up.
j. Confirm that the child will be
discharged to a home without lead
hazards.
B. Acetaminophen
1. Description
a. Seriousness of ingestion is determined
by the amount ingested and the length
of time before intervention.
b. Toxic dose is 150 mg/kg or higher in
children.
2. Assessment
a. First 2 to 4 hours: Malaise, nausea,
vomiting, sweating, pallor, weakness
b. Latent period: 24 to 36 hours; child
improves
c. Hepatic involvement: May last 7 days
and may be permanent; right upper
quadrant pain, jaundice, confusion,
stupor, elevated liver enzyme and
bilirubin levels, prolonged
prothrombin time
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