Page 108 - Clinical Pearls in Cardiology
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96  Clinical Pearls in Cardiology


                   •  Chronic mitral regurgitation—is usually high pitched
                     and radiates to the axilla
                   •  Chronic tricuspid regurgitation—is softer than that
                     of chronic mitral regurgitation. It is loudest at the left
                     lower sternal border and it increases in intensity with
                     inspiration
                   •  Ventricular septal defect—is loudest at the mid to
                     lower left sternal border, where it is usually
                     associated with a thrill and it radiates widely. There
                     is no change in intensity of the murmur with
                     respiration, but the intensity varies as a function of
                     the anatomic size of the defect (small defects
                     produce a loud murmur, whereas very large defects
                     produce a soft murmur).
                19.  How will you distinguish between the various short
                   systolic murmurs at the apical area?
                   The important short systolic murmurs heard at the
                   apical area are the murmurs of hypertrophic obstructive
                   cardiomyopathy (HOCM), mitral valve prolapse (MVP)
                   and papillary muscle dysfunction. Sometimes, the
                   murmur of valvular aortic stenosis is also best heard at
                   the apical area (especially in the elderly).
                   Dynamic auscultation is very helpful in differentiating
                   these short systolic murmurs at the cardiac apex. In
                   general, maneuvers which lead to a reduction in the size
                   of left ventricular chamber results in an increase in the
                   intensity of the murmurs of HOCM and MVP. But the
                   same maneuvers result in a decrease in the intensity
                   of the murmurs of papillary muscle dysfunction and
                   valvular aortic stenosis (Table 4).
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