Page 23 - Children Bookt.pdf

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If there is severe adverse reactions (Stevens - Johnson syndrome), severe liver disease,
severe anaemia, severe pancytopenia developed and if negative HIV status can be

Table ( 5 ) Doses of cotrimoxazole in infants and children
Suspension Single strength Double strength
Recommended Paediatric tablet
(5 ml syrup adult tablet adult tablet
daily dosage a (100 mg/20 mg)
200 mg /40 mg) (400 mg/ 80 mg) (800 mg/160 mg)
< 6 months ¼ tablet, possibly
2.5 ml One tablet ----
100 mg SMX /20 mg TMP mixed with feeding b
6 months – 5 years
5 ml c Two tablets Half tablet ----
200 mg SMX /40 mg TMP
> 6 – 14 years
10 ml c Four tablets One tablet Half tablet
400 mg SMX /80 mg TMP
> 14 years
800 mg SMX/ 160 mg ---- ---- Two tablets One tablet
TMP
Frequency - once a day

Notes:
a) Some counties may use weight bands to determine dosing. Age and corresponding
weight bands are

Age Weight

‡_ <5 kg

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5-15 kg

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15-30 kg
>14 years >30 kg

b) Splitting tablets into quarters is not considered best practice. This should be done
only if syrups are not available.
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tablets.

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