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A28    SCIENCE
                  Friday 21 december 2018
            U.S. urges doctors to write more Rx for overdose antidote




            By CARLA K. JOHNSON                                                                                                 community  programs  we
            AP Medical Writer                                                                                                   know are successful in sav-
            The  U.S.  government  told                                                                                         ing  lives,"  said  Dr.  Raeford
            doctors   Wednesday      to                                                                                         E. Brown Jr., who heads an
            consider  prescribing  medi-                                                                                        expert  panel  advising  the
            cations  that  reverse  over-                                                                                       FDA.
            doses  to  many  more  pa-                                                                                          The  new  guidance  tells
            tients who take opioid pain-                                                                                        doctors  to  consider  pre-
            killers in a move that could                                                                                        scribing  the  antidote  to
            add more than $1 billion in                                                                                         patients  on  high  doses  of
            health care costs.                                                                                                  opioids,  heavy  drinkers,
            Assistant   Secretary   for                                                                                         people  with  sleep  apnea
            Health  Brett  Giroir,  a  doc-                                                                                     and  other  breathing  prob-
            tor appointed by President                                                                                          lems, people taking benzo-
            Donald Trump, announced                                                                                             diazepines  such  as  Xanax
            the  guidance,  saying  it's                                                                                        and people with addiction
            important for doctors to dis-                                                                                       or mental health problems.
            cuss overdose dangers with                                                                                          It  expands  upon  a  similar
            patients.                                                                                                           recommendation  from  the
            Prescribing  naloxone  such                                                                                         Centers for Disease Control
            as  Narcan  along  with  opi-                                                                                       and Prevention. In April, U.S.
            oids  forces  a  conversation     In this Tuesday, July 3, 2018 file photo, a Narcan nasal device which delivers naloxone lies on a   Surgeon  General  Jerome
            that will lead to "a more in-  counter as a health educator gives instructions on how to administer it in the Brooklyn borough of   Adams  issued  the  office's
            formed decision by the pa-   New York.                                                                              first  national  public  health
            tient," he said.                                                                                   Associated Press  advisory in 13 years, calling
            The  action  comes  a  day                                                                                          on more Americans to start
            after  a  close  vote  from  a  be  an  investment  that  is  Naloxone  comes  in  a  na-  Critics  said  prescribing  the  carrying naloxone and urg-
            Food and Drug Administra-    well worth it," Giroir said.  sal spray, an injection and  antidote  to  pain  patients  ing more federal money to
            tion expert panel endorsing  More  than  47,600  Ameri-   an automatic injector. The  does not address the grow-    be dedicated to broaden-
            the  idea  of  rewriting  opi-  cans  died  of  opioid  over-  Narcan  nasal  spray  costs  ing share of fatal overdoses  ing  access.  Most  states  al-
            oid  drug  labels  to  include  doses  last  year,  a  toll  that  about $125 for a two-dose  caused  by  illicit  opioids,  low people to get naloxone
            a  naloxone  recommen-       has been rising for two de-  kit,  although  government  and could cause shortages  from  a  pharmacy  or  com-
            dation  for  many  or  all  pa-  cades. The street drug fen-  programs can get it for less.  for programs that hand out  munity  program  under  a
            tients.  An  FDA  document  tanyl is the top killer today,  The automatic injector can  the kits to street drug users.  statewide prescription and
            said  such  a  move  could  but  prescription  painkillers  cost as much as $4,000 per  It "will have the unintended  some states require doctors
            add more than $1 billion in  are still a problem, contrib-  kit,  although  its  maker  re-  consequence  of  derailing  to also prescribe naloxone
            health care costs.           uting to nearly 15,000 over-  cently authorized a cheap-  efforts  to  provide  nalox-  to patients on high doses of
            "Even  at  a  billion,  it  would  dose deaths last year.  er generic version.         one  to  the  very  effective  opioids.q


                                                                      Scientists lobby Mexico president over

                                                                      endangered porpoise



                                                                      By MARK STEVENSON            to  catch  totoaba,  a  fish  "This  is  the  only  practical
                                                                      Associated Press             whose swim bladder com-      option  for  effectively  en-
                                                                      MEXICO  CITY  (AP)  —  A  mands astronomical prices  forcing the law," wrote the
                                                                      group  of  prominent  sci-   and  is  considered  a  deli-  scientists, who included ex-
                                                                      entists  issued  an  appeal  cacy  in  China.  Vaquitas  perts like Barbara Taylor at
                                                                      Wednesday  to  Mexico's  become  entangled  in  the  the  U.S.  National  Oceanic
                                                                      new    president,   Andres  totoaba nets and drown.       and  Atmospheric  Admin-
                                                                      Manuel  Lopez  Obrador,  While the Mexican govern-        istration  and  Omar  Vidal,
                                                                      calling  on  him  to  take  the  ment  has  banned  the  use  formerly of the World Wild-
            In this July 8, 2017 file photo, a woman with the World Wildlife   unprecedented  step  of  of such nets in the vaquita's  life Fund.
            Fund  carries  a  paper  mache  replica  of  the  critically  endan-  outlawing the possession of  known  range,  the  rule  has  The letter also called on the
            gered porpoise known as the "vaquita marina" during an event   gill nets in the upper Gulf of  been  almost  impossible  to  government "to protect the
            in front of the National Palace calling on the government to take   California to save the criti-  enforce.         vaquitas that still remain," a
            additional steps to protect the world's smallest marine mammal,   cally  endangered  vaquita  So the scientists are calling  daunting task but one that
            in Mexico City.                                           porpoise.                    in  an  open  letter  to  Lopez  recent  research  suggests
                                                     Associated Press
                                                                      The  vaquita  is  the  world's  Obrador's top environmen-  can still be accomplished.
                                                                      smallest  and  most  endan-  tal officials that the govern-  A voyage by researchers in
                                                                      gered  porpoise,  and  lives  ment ban possession of the  late  September  sighted  six
                                                                      only in the Gulf, also known  nets in the whole area. The  or  seven  of  the  creatures,
                                                                      as  the  Sea  of  Cortez.  Ex-  researchers  also  called  for  including  a  mother  with  a
                                                                      perts say as few as 15 of the  land  patrols  and  inspec-  new calf.
                                                                      marine mammals remain in  tions  of  boats  setting  out  "Your  administration  can
                                                                      the  wild,  and  none  have  to sea to enforce the ban.  save  the  vaquita  and  set
                                                                      ever been held in captivity.  At  present,  authorities  pa-  an example for Mexico and
                                                                      The vaquita has been driv-   trol the area but poachers  the  world,"  the  scientists
                                                                      en  to  the  brink  of  extinc-  often flee in high-powered  wrote to Lopez Obrador.q
                                                                      tion by gill nets set illegally  boats and make it to shore.
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