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A28    SCIENCE
              Saturday 3 december 2016



















                 ‘Magic mushroom’ psychedelic may ease anxiety, depression


                                                                      cal  Center/New  York-Pres-  Bazer,  who  lives  in  New  mystical  experiences  ap-
                                                                      byterian Hospital. He didn’t  York,  was  diagnosed  with  peared to play a role in the
                                                                      participate in the work.     ovarian  cancer  in  2010,  drug’s therapeutic effect.
                                                                      Psilocybin,   also   called  when  she  was  63.  Treat-  Walcoff, 69, a psychothera-
                                                                      shrooms,  purple  passion  ment  was  successful,  but  pist in Rochester, New York,
                                                                      and  little  smoke,  comes  then  she  became  anxious  also entered the NYU study
                                                                      from certain kinds of mush-  about it coming back.        because  of  her  anxiety
                                                                      rooms. It is illegal in the U.S.,  “I  just  began  to  be  filled  over a cancer recurrence,
                                                                      and  if  the  federal  govern-  with  a  terrible  dread,”  she  in  her  case,  lymphoma.
                                                                      ment  approves  the  treat-  said in an interview. “You’re  (Most participants had ac-
                                                                      ment, it would be adminis-   waiting  for  the  other  shoe  tive cancer.)
                                                                      tered in clinics by specially  to  drop.  ...  (The  anxiety)  Psilocybin “opened me up
                                                                      trained staff, experts say.  was ruining my life.”        to  pursue  meditation  and
                                                                      Nobody should try it on their  She  swallowed  a  capsule  spiritual  searching,”  Wal-
                                                                      own, which would be risky,  of  psilocybin  in  2012  in  coff said, and as a result of
                                                                      said the leaders of the two  the  company  of  two  staff  that “I have become reas-
                                                                      studies, Dr. Stephen Ross of  members  trained  to  guide  sured  and  convinced  that
                                                                      New York University and Ro-  her  through  the  several  that phase of my life is over
            In this Monday, Nov. 28, 2016 photo Dinah Bazer poses at her
            home in New York.                                         land Griffiths of Johns Hop-  hours  that  the  drug  would  and it’s not going to come
                                                     Associated Press  kins University in Baltimore.  affect her brain. As she lis-  back.”
                                                                      Psychedelic  drugs  have  tened  to  music  through  Most funding for the studies
            MALCOLM RITTER               says  the  drug  experience   looked  promising  in  the  headphones, her eyes cov-    came from the Heffter Re-
             AP Science Writer           led her to begin a comfort-  past  for  treating  distress  in  ered with a sleep mask, the  search Institute, a nonprofit
            NEW YORK (AP) — The psy-     ing spiritual journey.       cancer patients. But studies  drug went to work.          organization  that  supports
            chedelic  drug  in  “magic  The  work  released  Thurs-   of  medical  use  of  psyche-  “Suddenly  I  was  in  a  dark,  studies  of  psilocybin  and
            mushrooms”  can  quickly  day  is  preliminary  and  ex-  delics stopped in the early  terrifying  place,  lost  in  other hallucinogens.
            and  effectively  help  treat  perts  say  more  definitive   1970s  after  a  regulatory  space, lost in time,” she re-  In  both  studies,  psilocybin
            anxiety  and  depression  in  research  must  be  done    crackdown  on  the  drugs,  called.  “I had no bearings  treatment had more effect
            cancer patients, an effect  on  the  effects  of  the  sub-  following  their  widespread  and I was really, really ter-  on anxiety and depression
            that  may  last  for  months,  stance,  called  psilocybin   recreational  use.  It  has  rified.”  Then  she  saw  her  than  a  placebo  did.  For
            two small studies show.      (sih-loh-SY’-bihn).          slowly  resumed  in  recent  dread  of  a  cancer  recur-  example, by the day after
            It  worked  for  Dinah  Bazer,  But the record so far shows   years.                   rence  as  a  black  mass  in  treatment,  about  80  per-
            who  endured  a  terrifying  “very  impressive  results,”   Griffiths  said  it’s  not  clear  her abdomen, and she fu-  cent  of  the  treated  NYU
            hallucination  that  rid  her  said  Dr.  Craig  Blinderman,   whether  psilocybin  would  riously yelled at it to leave.  patients  no  longer  quali-
            of the fear that her ovarian  who  directs  the  adult  pal-  work outside of cancer pa-  “As  soon  as  that  hap-  fied  as  clinically  anxious
            cancer  would  return.  And  liative  care  service  at  the   tients, although he suspects  pened, the fear was gone,”  or  depressed  by  standard
            for  Estalyn  Walcoff,  who  Columbia  University  Medi-  it might work in people fac-  she said. “I was just floating  measures.  That  compares
                                                                      ing  other  terminal  condi-  in  the  music  ...  like  being  to about 30 percent for the
                                                                      tions. Plans are also under-  carried in a river.”        placebo group. That’s a re-
                                                                      way  to  study  it  in  depres-  Then she felt deep love for  markably fast response, ex-
                                                                      sion  that  resists  standard  her family and friends, and  perts  said,  and  it  endured
                                                                      treatment, he said.          sensed  their  love  for  her.  for the seven weeks of the
                                                                      The new studies, published  “It felt like I was bathed in  comparison.
                                                                      in  the  Journal  of  Psycho-  God’s  love  ...  I’m  still  an  The  studies  took  different
                                                                      therapy, are small. The NYU  atheist,  by  the  way,  but  approaches  for  formulat-
                                                                      project,  which  also  includ-  that  really  seemed  to  be  ing a placebo. At NYU, pa-
                                                                      ed  psychotherapy,  cov-     the  only  way  to  describe  tients  were  given  niacin,
                                                                      ered  just  29  patients.  The  it.”                      which mimics some effects
                                                                      Hopkins study had 51.        Researchers    said   such  of psilocybin.q
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