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                                                                        innumerable  researches  conducted
                                                                        throughout the Globe. Several genes
                                                                        both functional and non-functional have
                                                                        been identified and mapped. A huge
                 Exploring  Genomics                                    number of SNPs have been detected
                                                                        in chicken genome. But, main aim of
                     for Revolution in                                  the  genomic  study  is  to  utilize  the
                                                                        genomic information for  uncovering
                   Poultry  Production                                  several  physiological  phenomenon
                                                                        involved in maintaining living systems.
                                                                        In  fact,  all  biological  pathways  are
                                                                        dependent on enzymes and co-factors.
       Till date, a huge collection of genomic information in poultry is available,  The enzymes are protein in nature
       which has been the outcome of innumerable researches conducted throughout  and  these proteins  are  encoded  by
       the Globe                                    —By Dr Som Dutt     genes and hence, protein molecule is
                                                                        the  most  important  fundamental
       Chicken genomics has been the first  genscan gene prediction reports reveal  particle present in the living beings.
       study performed among all the farm  the presence of approximately 40,505  Without  protein,  nothing is  possible
       animals  after  initiation  of  Human  genes in chicken genome.  and there will be no existence of life.
       Genome Project. Keeping importance  The  total  number  of  single  The proteins derived from genes
       of  chicken  in  farm  livelihood,  the  nucleotide  polymorphism  found  in  and phenotypes derived from proteins
       species   was    selected   for  genes was about 3,202,570. Thus, a  are  basic  principles  of  functional
       accomplishment of Chicken Genome  huge genomic information is currently  genomic study. To understand different
       project.  The  total genomic  length  of                         biological  pathways,  to  identify  the
       chicken  is  1.2X10  6  bp  in  which                            genes involved in controlling a specific
       approximately  4,782  genes  are          In Brief               character, to explore the participation
       present.                           Chicken genomics has been    of genes in growth and development
       EXPLORING CHICKEN GENOMICS           the  first  study  performed  of various organs/systems/tissues/
       The  study  of  ESTs,  global  gene  among all the farm animals.  cells and to detect genetic marker for
       expression profiling etc. performed to                           specific trait, functional genomics hold
       establish  metabolic  pathways  and   Several  genes  regulate  egg  an enormous prospect. A number of
       functional mapping for localization of  production   and   meat  genomics tools are being considered
       gene  on  the  chromosome.  Several  production in chicken.      of which the most important ones are
       genes  regulate  egg  production and   Genomics  in  poultry  has  expressed sequence tag (EST), global
       meat production in chicken. The study  bright  future  to  augment  gene   expression   profiling,
       of these  genes will explore genetic  productivity at a faster rate.  identification  of  functional  genes,
       markers for the traits to be further used   Till date, a huge collection of  functional mapping and genetic marker.
       in selection programme and to produce  genomic  information  in  These tools are essential to intersect
       genetically  superior  animals  having  poultry is available.    the  chicken  genome  so  that
       potential of enriched egg production/   A huge number of SNPs have  physiological  and  biochemical
       meat  production/egg protein/meat    been  detected  in  chicken  pathways are unravelled. The molecular
       protein/low egg cholesterol/low meat                             mechanisms are to be defined first so
       cholesterol etc.                     genome.                     that the key events are modulated as
          Genomics  in  poultry  has  bright                            per  the  desire  of  the  farmers,  for
       future to  augment  productivity at  a  available with us and now, the prime  example production of protein rich egg
       faster rate in poultry sector. The genetic  focus  of  molecular  biologists  is  to  and  meat,  low  cholesterol  egg  and
       mechanism      that    governs  explore gene-function relationship in  meat,  PUFA  enriched  egg  etc.  The
       multiplication, differentiation, growth  regulating  metabolic  pathways  and  status of the genomic tools in chicken
       and function in chicken are not fully  guiding the process  of  transcription  has been described below in brief.
       uncovered.  The  number  of  non-  and  translation  of  RNA  molecules,  The ESTs are nothing but the partial
       functional or pseudogenes identified  DNA replication and cell division, and  sequences of transcripts expressed in
       is about 96, while the number of RNA  finally, cell to cell communication for  specific   tissues,   which   are
       genes is about 650. The total number  expressing the traits or phenotypes.  representatives  of  specific  gene
       of  exons  across  the  whole  chicken  PURSUING A NOBLE PURPOSE  transcripts. Initially, cDNA libraries are
       genome is reported as about 1,80,000  Till date, a huge collection of genomic  prepared for specific tissue and high
       from which 22,290 gene transcripts  information  in  poultry  is  available,  through put sequencing is done on the
       have  been  predicted.  However,  which  has  been  the  outcome  of  clones.
       March 2018                                                                  Competition  Wizard  75
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