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746 SECTION VII Endocrine Drugs
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C ASE STUD Y ANSWER
The patient should be advised to start daily transdermal and normal monthly uterine bleeding resume. She should
estradiol therapy (100 mcg/d) along with oral natural pro- also be advised to get adequate exercise and increase
gesterone (200 mg/d) for the last 12 days of each 28-day her calcium and vitamin D intake as treatment for her
cycle. On this regimen, her symptoms should disappear osteoporosis.