Page 816 - Atlas of Histology with Functional Correlations
P. 816
Formed by tight junctions of adjacent Sertoli cells
Separates seminiferous tubules in basal and adluminal compartments
Protects developing sperm from autoimmune response and harmful materials
MALE HORMONES
Spermatogenesis dependent on luteinizing and follicle-stimulating hormones
produced by the pituitary gland
Luteinizing hormone binds to receptors on interstitial cells and stimulates
testosterone secretion
Follicle-stimulating hormone stimulates Sertoli cells to produce androgen-
binding hormone into seminiferous tubules to bind testosterone
Testosterone in seminiferous tubules is vital for spermatogenesis and
accessory gland function
Sertoli cells produce inhibin to inhibit FSH production and activin to release
FSH from pituitary gland via negative feedback
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