Page 29 - Pharmaceutical Organic Chemmistry-3 (Theoritical book) 24-25
P. 29

Clinical Pharmacy PharmD - 2024/2025                  Level 2                Pharmaceutical Organic Chemistry-3 (PC 305)
            Prefix of attached component to the parent ring


            Pyrazole ---------> pyrazolo      Indole ----------> indolo  Pyran --------> pyrano
            Exception:


            Furan --------------> furo                               thiophene ----------> thieno

            Imidazole ---------> imidazo                          quinazoline ---------> quino

            Pyridine -----------> pyrido                            isoquinoline --------> isoquino

            Pyrimidine --------> pyrimido                        naphthalene ---------> naphtho

            Benzene -----------> benzo                              benzofuran ----------> benzofuro



            Rule 5:

               1)  If a heteroatom is common to both rings, it must be considered as a member of

                   both rings.

               2)   By  numbering  of  such  compounds,  the  common  heteroatom  takes  its  own

                   number,  in  contrast  to  carbon  atoms  in  the  fusion  position,  which  are  not

                   numbered
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