Page 29 - Pharmaceutical Organic Chemmistry-3 (Theoritical book) 24-25
P. 29
Clinical Pharmacy PharmD - 2024/2025 Level 2 Pharmaceutical Organic Chemistry-3 (PC 305)
Prefix of attached component to the parent ring
Pyrazole ---------> pyrazolo Indole ----------> indolo Pyran --------> pyrano
Exception:
Furan --------------> furo thiophene ----------> thieno
Imidazole ---------> imidazo quinazoline ---------> quino
Pyridine -----------> pyrido isoquinoline --------> isoquino
Pyrimidine --------> pyrimido naphthalene ---------> naphtho
Benzene -----------> benzo benzofuran ----------> benzofuro
Rule 5:
1) If a heteroatom is common to both rings, it must be considered as a member of
both rings.
2) By numbering of such compounds, the common heteroatom takes its own
number, in contrast to carbon atoms in the fusion position, which are not
numbered