Page 75 - Pharmaceutical Organic Chemmistry-3 (Theoritical book) 24-25
P. 75
Clinical Pharmacy PharmD - 2024/2025 Level 2 Pharmaceutical Organic Chemistry-3 (PC 305)
A monosaccharide containing an aldehyde group is called an aldose;
One containing a ketone group is called a ketose.
These two classifications are frequently combined.
A C 4 aldose, for example, is called an aldotetrose; a C 5 ketose is called a ketopentose.
➢ D and L Designations of Monosaccharides
The simplest monosaccharide which has chiral center is glyceraldehyde.
It exists in two enantiomeric forms that have the absolute configurations shown here:
(+)-glyceraldehyde is designated (R)(+)-glyceraldehyde and (-)-glyceraldehyde is
designated (S)(-)-glyceraldehyde.
The D–L system of stereochemical designations has the disadvantage of specifying the
configuration of only one chiral center that of the highest numbered chirality center.
