Page 31 - Annual report 2021-22
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Annual Report 2021-22 |
into optic cups and mature photoreceptors, analysis of the mature photoreceptors from RP-iPSC lines
show degeneration in terms of outer nuclear layer thickness and reduction in photoreceptor markers
RECOVERIN and RHODOPSIN on day 150 and not day 120. The results suggest that the gene editing
analysis may have to be carried out later than day 150 post- differentiation.
In collaboration with Sridhar Sivasubbu, he was also involved in the genomic testing for over 1200
14
samples collected from individuals suffering from/carrier for sickle cell disease.
“For the birth of something new, there has to be a happening. Newton
saw an apple fall; James Watt watched a kettle boil; Roentgen fogged
some photographic plates. And these people knew enough to translate
ordinary happenings into something new.” — Alexander Fleming