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International Conference on

Recent Trends in Environmental Sustainability

ESCON22/FWSH/17
Prevalence, clinical presentation and staphylococcus aureus related co-infections in
dengue patients

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Sania Tasawar , Muhammad Idrees *, Zeenat Haq
1 Department of Biosciences, University of Wah
Correspondence: idreesalvi@gmail.com
Abstract

Dengue fever is an important mosquito-borne disease with a highly variable clinical spectrum,
ranging from self-limiting mild illness to expanded dengue syndrome (EDS). Four dengue
serotypes known as DENV-1, -2, -3, and -4 can cause severe and fatal diseases. They all are
spread by species of mosquito known as Aedes aegypti and more rarely by the Aedes
albopictus mosquito. During recent years, Staphylococcus aureus has emerged as an important
bacterial pathogen causing DDIs (Dengue dual infections). The aim of the study was to assess
the occurrence of S. aureus in patients with prolonged dengue fever. In this study we analyze
the clinical and pathological data of patients infected with dengue. Characters of these strains
were determined by cell morphology and standard biochemical tests. Antibiotic susceptibility
was carried out by disc agar diffusion test, minimum inhibitory concentration, and minimum
bactericidal concentration. Two hundred and four (204) patients aged up to eighty (80) years
were studied out of which ninety-six (96) were suffering from coinfection with S. aureus.
Multidrug resistance was detected in the S. aureus strains. Our results indicate that multidrug
resistant S. aureus may be associated with dengue in studied population. It highlights the
importance of bacteria in exacerbating dengue infections and the importance of looking for co-
infection in patients with certain clinical manifestations.
Keywords: Dengue; Pakistan; S. aureus; Mosquito; Coinfection

Department of Environmental Sciences, COMSATS University Islamabad, Vehari Campus

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