Page 25 - Headlines Histology2024_Neat

• The cells reaching the surface are either ciliated or goblet cells.
• The short cell acts as progenitors for the tall cells.
• The pseudostratified columnar ciliated epithelium may be differentiated

from the stratified epithelium by: 1) cilia are never exists on stratified
epithelium. 2) The apical cytoplasm of the cell forming the pseudostratified
epithelium does not contain nuclei.
• Locations: in reproductive and respiratory epithelium.

STRATIFIED EPITHELIUM

• It consists of two or more than two layers of cells.

Stratified squamous epithelium
• It consists of several layers of cells with only the superficial cells having
squamous shape.

Stratified squamous non-keratinized epithelium
• It consists of three layers:
• Stratum Basale is a single layer of cuboidal to columnar cell rest on a wavy
basement membrane.
• Stratum spinosum is composed of several layers of polyhedral cells tightly
adhere to each other by numerous desmosomes. In H&E sections, the
desmosomal attachments appear as small spiny processes, hence the name
of this layer (spiny layer or stratum spinosum). The stratum basale and the
deep layer of stratum spinosum are involved in active mitosis, therefor this
region is referred to as stratum germinativum.
• Stratum squamosum is the superficial layer and is made up of few layers of
flat squamous cells with ovoid small nuclei.
• Locations: oral cavity, pharynx, esophagus, anal canal, and vagina. Such
sites are normally subjected to moderate mechanical abrasion and are kept
moist by local glandular secretions.

Stratified squamous keratinized epithelium
• It consists of five layers:

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