Page 30 - Headlines Histology2024_Neat
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• They are non-motile and readily visible with LM on the epithelium lining
       the epididymis.

   • It facilitates absorption through increase the surface area.

III.INTERCELLULAR SURFACES (LATERAL SURFACES)

Cell junctions and junctional complex
   • The cell junction holds epithelial cells together and is composed of four
       different types:

Zonula occludens (tight junctions)
   • It is located just below the luminal surface and consists of small areas
       where the outer laminae of opposing plasma membranes are fused with
       each other.
   • As the term zonula (belt-like) implies, the tight junction forms a complete
       circumferential belt around each cell thus sealing the intercellular space
       from the lumen.

Zonula adherens
   • It is located deep to the tight junctions forming a circumferential belt
       (zonula) around each cell.
   • At these areas, the opposing plasma membranes diverge; no structures are
       evident between the opposing cell membranes.
   • On the cytoplasmic aspect of these junctions, there is a fine network of
       filamentous materials that fuse with the filaments of the terminal webs.

Macula adherens (desmosomes)
   • The term macula indicates that the junctional area is in the form of spot-
       like.

   • It constitutes the third component of the junctional complex but also occurs
       singly at many intercellular sites.

   • At the desmosome, the opposing plasma membranes are separated by a gap
       in which several fine, transverse filaments or dense longitudinal line may be
       seen.

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