Page 10 - Microbiology in workplace
P. 10

GMP Training – Microbiology in the Workplace by www.gmpsop.com

               Overview

               To properly control micro-organisms, we need to understand what makes them
               grow and multiply.


               Micro-organisms only need small amounts of nutrients and moisture to grow,
               which is why manufacturing facilities need to be kept clean and dry.

               The growth of micro-organisms depends on the combination of the below factors:

                   Nutrients


                   Moisture

                   Physical environment



                                         GROWTH OF MICRO-ORGANISMS


                                           Nutrients

                                           The main nutrients are:


                                               Carbon,  from  carbon  dioxide  (CO2)  or  organic
                                               compounds


                                               Nitrogen, from organic compounds such as amino
                                               acids, and inorganic compounds such as ammonia

                                               Hydrogen, oxygen, sulphur, and phosphorus, which
                                               are all found in water and the atmosphere.



                                           Moisture

                                           Just like humans, micro-organisms need water to grow.
                                           Water  is  responsible  for  a  large  majority  of  a  cell's
                                           makeup,  and  has  roles  in  nutrition  and  cellular

                                           metabolism.









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