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SSTI Develop diagnostic Avoid empiric use of Uncomplicated
criteria to distinguish antipseudomonal beta- bacterial cellulitis can
purulent and non- lactams and/or anti- be treated for 5 days if
purulent infections and anaerobic agents unless there is a timely clinical
severity of illness (i.e., clinically indicated. response.
mild, moderate and
severe) to ensure
infections can be
treated appropriately
according to guidelines.

AMS also can be done by focusing on certain broad-spectrum antibiotic, especially reviewing
when it was started as empirical therapy. Three important questions can be used when
reviewing are:
• Is the antibiotic still needed?
• If so, is the antibiotic tailored to the culture results (e.g. is the narrowest spectrum agent
being used?)
• How long the antibiotic should be used?

Daily activities done by pharmacists are also a part of AMS, such as:
• Monitor response to antibiotic therapy with feedback to the treating clinician.
• Review unnecessary polypharmacy of the same antimicrobial coverage.
• Opportunities for IV to PO switch.
• Monitor safety of antimicrobial therapy (e.g. renal dose adjustment and drug-drug
interaction).

Any AMS activities can be incorporated appropriately where applicable.

Second Edition 2022 | Protocol on Antimicrobial Stewardship (AMS) Programme in Healthcare Facilities 39