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Clinical pharmacy 2024/2025                   Level 2 Pharm D                       Physiology and Pathophysiology (MD303)

                                                                 Countercurrent Multiplier System

                ✓  Multiplies the [interstitial fluid] and [descending
                    limb fluid].
                ✓  Flow in opposite directions in the ascending and
                    descending limbs.

                ✓  Close proximity of the 2 limbs:
                ✓  Allows interaction.
                ✓  Positive feedback.




                                                          Osmolality of Different Regions of the Kidney





























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