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Clinical pharmacy 2024/2025                            Level 3 Pharm D                             Pharmacology 1 (PO 502)
            2-  Inhibition of cytochrome P450 → interfere with the metabolism of drugs such as

               phenytoin, tolbutamide, warfarin, fluvastatin and tamoxifen if taken concomitantly.
            3-  Serious hematological adverse effects “neutropenia, thrombocytopenia, and
               aplastic anemia) limit ticlopidine usefulness.

































































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