Page 93 - Phytochemistry 2 (06-PG 605)

Chemically, vinca alkaloids are indole or indoline derivatives. They
are classified into two main groups:
1) Monomeric alkaloids: catharanthine and vindoline.
2) Dimeric alkaloids: vinblastine and vincristine.

They are sub divided into:
a) Indole monomeric alkaloids (catharanthine-type): e.g.
catharanthine
b) Indoline monomers (vindoline-type): e.g. vindoline
c) Dimeric indole-indoline type.

Monomeric Vinca Alkaloids

N

N

N *
H3COOC
H3CO N HO OCOCH3
COOCH3
CH3
*
Vindoline
Catharanthine

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