Page 3 - Pharmaceutics-II (02-06-01 203)

Table of content:

SUPPOSITORIES ......................................................................................................... 4
Definition, different types and shapes........................................................................... 5
Location of action....................................................................................................... 6
Advantages of suppositories ........................................................................................ 7
Disadvantages of suppositories .................................................................................... 7
Physiological factors influence the drug absorption from rectal suppositories. ................ 7
Composition of suppositories....................................................................................... 8
Suppository bases (the vehicle) .................................................................................... 9
Preparation of suppositories.......................................................................................14
Packaging and storage ...............................................................................................18
Testing of suppositories (quality control tests)..............................................................18
Liquid suppositories ..................................................................................................20

Topical Semi Solid Dosage Forms...................................................................................21
Intended Learning Outcomes .....................................................................................21
Recommended References..........................................................................................21
What are semi solid dosage forms? ...............................................................................21
Ideal properties of semi-solid dosage forms ...................................................................22
Formulation of semi-solid dosage forms: ......................................................................22
Types of semi-solid dosage preparations:.......................................................................22
Ointments .................................................................................................................22
Creams .....................................................................................................................26
Gels ..........................................................................................................................27
Pastes .......................................................................................................................30
Poultices (Cataplasm) ................................................................................................30
Plasters......................................................................................................................31
Dressings ..................................................................................................................31
Rigid foams...............................................................................................................32
Additives used in Semi Solid Preparations .....................................................................32
Selection of the appropriate base:.................................................................................34
Novel advances is semisolid dosage forms:...................................................................35
Evaluation of semisolid dosage forms:.........................................................................35

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