Page 25 - phytochemistry II -pharmD general

12.Treatment of bronchial asthma : e.g. Ephedrine & theophylline
13.Miotic effect: e.g. physostigmine (Eserine), Pilocarpine
14.Mydriatic: e.g. atropine,Hyoscyamine
15.Sedative: e.g. Scopolamine (Hyoscine)
16.Treatment of cerebral vascular deficiency and atherosclerosis (Geriatric
medicine) e.g. Vincamine
17.Hallucinogenic : e.g. Mescaline,Psilocin.

Proto alkaloids (Non-heterocyclic alkaloids)

The nitrogen atom in the alkaloids of this group is not involved in heterocyclic
ring.
I- Alkaloids of the phenylalkylamine group
II- Tropolone alkaloids (Colchicine )
III-Diterpene alkaloids (Taxol)

I- Alkaloids of the phenylalkylamine group

The principle alkaloids of this group which have pharmacological activity
are
Ephedra, Cathe, Peyote and Capcicum alkaloides.

1- Ephedra alkaloids
Ephedrine

Ephedrine occurs in E. sinica and in E. equisetina and associated with d--
ephedrine in E. vulgaris.

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