Page 30 - phytochemistry II -pharmD general
P. 30
II Tropolone alkaloids
7 membered unsaturated ring structure (Tropolone)
Colchicine MeO AB O
Sources: MeO OMe C NH - C - CH3
O
O - Me
seeds of Colchicum autumnale(Liliaceae).
properties:
It is an amorphous yellowish- white powder.
It is neutral alkaloid & may be extracted from either acidic or alkaline solution by
CHCl3.
• With conc. acids Allocolchicine (Colchicic acid methyl ester)
(ring C →benzenoid)
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