Page 92 - phytochemistry II -pharmD general
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Other Related Simple Tryptamine Derivatives
1. Melatonin: H2 H2 NH
C C
H3CO
N OC CH3
H
Melatonin is (N-acetyl-5-methoxytryptamine). It is a hormone, naturally occurring
in most animals, including humans, and some other living organisms, including
algae. Circulating levels vary in a daily cycle, and melatonin is important in the
regulation of the day hour's variations of several biological functions.
2. Psilocin and Psilocybin
R
NMe2
N
H
R= OH Psilocin
R= OPO3H2 Psilocybin
Psilocin is a psychedelic (hallucinogenic) alkaloids. It is found in most
psychedelic mushrooms together with its phosphorylated counterpart psilocybin.
The red sacred mushrooms, Psilocybe mexicana, contain 0.2-0.4% of psilocybin
and traces of psilocin.
Action and uses
They are hallucinogenic narcotic alkaloid, may cause serious psychologic
disturbances.
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