Page 91 - Medicinal Plants_PharmD general

1. Glycolysis

1 glucose molecule  2 pyruvate, 2 NADH & 2 ATP

2. Pyruvate oxidation

Each pyruvate from glycolysis enters the mitochondrial matrix. A carboxyl
group is removed from pyruvate and released as a molecule of carbon
dioxide, leaving behind a two-carbon molecule which is then oxidized, and
the electrons lost in the oxidation are picked up by NAD+ to form NADH.
The oxidized two-carbon molecule (an acetyl group) is attached to
Coenzyme A (CoA), to form acetyl CoA.
2 Pyruvate produce 2 acetyl CoA, 2 CO2 and 2 NADH

3. Citric acid (krebs) cycle in mitochondrial matrix

Each Acetyl CoA (one turn of cycle) produces 3 NADH, 1 FADH2, 2 CO2,
1 ATP
Since 1 glucose by glycolysis produces 2 pyruvate which in turn produce
2 acetyl CoA, citric acid cycle produces in total 6 NADH, 2 FADH2, 4 CO2,
2 ATP

 Each glucose molecule (in the 3 previous step) produces 10 NADH,
2 FADH2, 4 ATP, 6 CO2

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