Page 133 - Applied Pharmacognosy
P. 133

Types of Chemical markers

• It is a method of analysis suitable for qualitative and quantitative

   analysis of volatile components in solid or liquid samples.

• The method is based on the analysis of the vapor phase in

   equilibrium with the solid or liquid phase.

• Head-space chromatography is the method of choice for

   determining residual solvents in pharmaceutical drugs. Such as
   limit of chloroform and ethylacetate in colchicine.
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