Page 351 - Applied Pharmacognosy

Redefining QualiTtyyp-QesuaolfitCyhIesmsuiceasl mwiathrkHeresrbs

 Bad Manufacturing Practices

 Cases of cardiotoxicity resulting from the ingestion of

Aconitum speciesusedintraditionalChinesemedicine

(TCM)havebeenreportedfrom HongKong.

 InTCM,Aconitum rootstocksareprocessed bysoaking
orboilingthem inwater in order to hydrolyzethe
aconitinealkaloidsintotheirlesstoxicaconine
derivatives.

 Toxicity can result when such processes are
uncontrolled and invalidated.IntheUK,theinternal
useofaconiteisrestrictedto prescriptiononly .