Page 89 - Clinical Biochemistry
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Figure 58: Dialysis
2-Renal transplantation
Acute Renal Failure Chronic Renal Failure
Failure of renal function over a It develops over months or years and lead to end stage
period of hours or days renal failure.
It is reversible and normal Irreversible destruction of kidney tissues by disease may
function regained. be treated by dialysis or transplant.
Oliguria, metabolic acidosis, The patient with CRF may be without symptoms until
hyperkalemia. GFR failsto very low values symptoms:
Determined by Polyuria.
• increased urea and creatinine Hyperkalaemia
levels •Abnormal Ca and P metabolism.
Anemia (failure of erythropoietin production).
• decreased urine volume (less
than 400 ml/24 hrs).
Renal Function Tests
Why needed:
• To assess functional capacity of kidney.
• To diagnose renal impairment.
• To assess the degree of severity and progression of renal impairment.
• To assess the effectiveness of treatment.
