Page 87 - Pharmaceutics III_ 02-06-01304_Fall 2025_ Pharm D_Electronic book

Test Acceptance Criteria

Weight variation ±5 %

Friability ≤1 %

Disintegration ≤15 min

Dissolution ≥80 % in 30 min

Content uniformity 85–115 % of label claim

Analytical Techniques Used:
• UV–Visible spectrophotometry.
• HPLC.
• FTIR for compatibility.
• DSC for polymorphism.
• Karl Fischer titration for moisture.

Storage and Transport:
• Maintain temperature <25 °C.
• Relative humidity <60 %.
• Protect from light and mechanical stress.

Future Trends in Tablet and Capsule Technology:
1. 3D printing of pharmaceuticals.
2. Orally disintegrating films.
3. Osmotic-controlled release systems.
4. Multiparticulate capsules with mini-tablets.
5. Nanotechnology-enabled tablets.
6. Continuous manufacturing.

Emerging Coating Technologies:
• Electrostatic coating.
• Hot-melt coating.

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