Page 88 - Pharmaceutics III_ 02-06-01304_Fall 2025_ Pharm D_Electronic book
P. 88
• Supercritical fluid coating.
• Automated closed-pan systems with real-time monitoring.
Continuous Manufacturing Concept:
Integration of raw material feeding, blending, granulation, drying, and compression in
continuous line.
Advantages:
• Reduced production time.
• Real-time quality assurance.
• Lower cost and variability.
Tablet and Capsule Innovations:
• Floating tablets for gastric retention.
• Mucoadhesive tablets for local delivery.
• Pulsatile-release systems.
• Multi-particulate pellet-filled capsules.
Summary:
Tablet and capsule manufacturing requires control over formulation, processing, and testing
parameters to ensure consistent product quality, efficacy, and safety. Compliance with GMP,
QbD, and validation principles forms the foundation of modern pharmaceutical production.
87
