Page 553 - Applied Pharmacognosy

7. Oxidation and reduction reactions: 552

c) Oxygenases:

These catalyse the direct addition of oxygen from O2 to the substrate; they
are subdivided into:

* Mono-oxygenases;

• These introduce one O atoms from molecular oxygen into the substrate.

• The second O from O2 is reduced to water by NADH or NADPH.
• Cytochrome P-450 mono-oxygenases are typical examples and are

involved in hydroxylation.