Page 52 - Pharm.Org.Chem-I 02-06-05-101
P. 52

Racemic mixture (±)
 ❑ It is a mixture of 2 enantiomers
 with the same amount, each rotates
 the plane-polarized light by the
 same amount, but in the opposite
 direction.
 ❑ Racemic mixtures are optically
 inactive i.e. they cancel each other
 and are denoted by (±).

99

    Specific rotation ([α]D)

The amount of rotation
depends on:

   sample concentration
   sample path length
   temperature
   wavelength of the light

100

                                       50
   47   48   49   50   51   52   53   54   55   56   57